Quantification of proteins and metabolites by mass spectrometry without isotopic labeling or spiked standards

…, S Norton, P Kumar, M Anderle, CH Becker - Analytical …, 2003 - ACS Publications
A new method is presented for quantifying proteomic and metabolomic profile data by liquid
chromatography−mass spectrometry (LC−MS) with electrospray ionization. This …

Global changes to the ubiquitin system in Huntington's disease

…, B Woodman, KY Ryu, TS Zaitseva, CH Becker… - Nature, 2007 - nature.com
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by
expansion of CAG triplet repeats in the huntingtin (HTT) gene (also called HD) and …

Matrix‐assisted laser desorption time‐of‐flight mass spectrometry of oligonucleotides using 3‐hydroxypicolinic acid as an ultraviolet‐sensitive matrix

KJ Wu, A Steding, CH Becker - Rapid Communications in Mass …, 1993 - Wiley Online Library
Matrix‐assisted laser desorption time‐of‐flight mass spectrometry has been used to produce
quasimolecular ion signals from underivatized mixed‐base single‐stranded DNA oligomers …

Protein standard absolute quantification (PSAQ) method for the measurement of cellular ubiquitin pools

…, BE Riley, TA Shaler, RS Trevino, CH Becker… - Nature …, 2011 - nature.com
The protein ubiquitin is an important post-translational modifier that regulates a wide variety
of biological processes. In cells, ubiquitin is apportioned among distinct pools, which include …

The quadruple gravitational lens PG 1115+ 080: Time delays and models

…, R Barr, R Barvainis, CM Becker… - The Astrophysical …, 1997 - iopscience.iop.org
Optical photometry is presented for the quadruple gravitational lens PG 1115+ 080. A preliminary
reduction of data taken from 1995 November to 1996 June gives component C leading …

[PDF][PDF] High-throughput DNA analysis by time-of-flight mass spectrometry

JA Monforte, CH Becker - 1997 - researchgate.net
JOSEPH A. MONFORTE & CHRISTOPHER H. BECKER GeneTrace Systems Inc., 333
Ravenswood Avenue, Menlo Park, California 94025–3493, USA called matrix-assisted laser-…

Single nucleotide polymorphism determination using primer extension and time‐of‐flight mass spectrometry

…, DJ Pollart, JA Monforte, CH Becker - …, 1999 - Wiley Online Library
The high frequency of single nucleotide polymorphisms (SNPs) in the human genome
makes them a valuable source of genetic markers for identity testing, genome mapping, and …

3H Dendrimer Nanoparticle Organ/Tumor Distribution

…, A El-Jawahri, TS Lawrence, CW Becker… - Pharmaceutical …, 2004 - Springer
Purpose. To determine the in vivo biodistribution for differently charged poly(amidoamine) (PAMAM)
dendrimers in B16 melanoma and DU145 human prostate cancer mouse tumor …

Protein biomarker identification in the CSF of patients with CNS lymphoma

…, MA Shuman, T Jones, CH Becker… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Elucidation of the CSF proteome may yield insights into the pathogenesis of CNS
disease. We tested the hypothesis that individual CSF proteins distinguish CNS lymphoma …

Surface analysis by nonresonant multiphoton ionization of desorbed or sputtered species

CH Becker, KT Gillen - Analytical Chemistry, 1984 - ACS Publications
A general method of surface analysis by laser Ionization (SALI) Is presented. In this high-vacuum-based
method, a small fraction of a monolayer Is desorbed or sputtered from a surface …