The role of the Notch signaling pathway in neural development has been well established
over many years. More recent studies, however, have demonstrated that Notch continues to …

PURPOSE Some cases of hemichorea-hemiballism (HCHB) are associated with a hyperintense
putamen on T1-weighted MR images, the cause of which remains unclear. Our purpose …

94.92 (1); R= 0.0432. The structures of 4 and 5 are similar; each has linear, two-coordinate
gold atoms connected via a bridging bis (phosphine) to form an open-chain dinuclear …

BACKGROUND The purpose of the current study was to investigate a hospital series of 986
cases of primary pediatric brain tumors in Taiwan. METHODS The authors reviewed the …

9,10,11,20,21,22-Hexaphenyltetrabenzo[a,c,l,n]pentacene (1) was prepared by the reaction
of 1,3-diphenylphenanthro[9,10-c]furan with the bisaryne equivalent generated from 1,2,4,5-…

Fifty‐one primary intracranial germ cell tumors (GCT), including germinoma, teratoma,
endodermal sinus tumor, choriocarcinoma and mixed GCT, were studied. The incidence of GCT in …

Eleven atypical teratoid/rhabdoid tumors (AT/¶RT) and 121 primitive neuroectodermal
tumors/medulloblastomas (PNET/MB) were included in this study for evaluation of the …

Octaphenylnaphthalene (2) was synthesized by the addition of tetraphenylbenzyne to
tetraphenylcyclopentadienone, and decaphenylanthracene (3) was synthesized by the addition of …

SAR on HTS hits 1 and 2 led to the potent, Notch-1-sparing GSI 9, which lowered brain Aβ
in Tg2576 mice at 100 mg/kg po. Converting the metabolically labile methyl groups in 9 to …

Xenopus tadpoles can fully regenerate all major tissue types following tail amputation. TGF-β
signaling plays essential roles in growth, repair, specification, and differentiation of tissues …