User profiles for David Malik
David J. MalikChancellor's Professor Emeritus, Indiana University Purdue University Indianapolis Verified email at iupui.edu Cited by 728 |
Diagnostic accuracy of noninvasive fibrosis models to detect change in fibrosis stage
…, AM Diehl, C Kigongo, M Kopping, D Malik… - Clinical …, 2019 - Elsevier
Background & Aims Noninvasive methods are needed to determine disease stage in patients
with nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic performance of …
with nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic performance of …
[PDF][PDF] Multicenter validation of association between decline in MRI‐PDFF and histologic response in NASH
…, AM Diehl, C Guy, C Kigongo, M Kopping, D Malik… - …, 2020 - Wiley Online Library
Background and Aims Emerging data from a single‐center study suggests that a 30% relative
reduction in liver fat content as assessed by magnetic resonance imaging–proton density …
reduction in liver fat content as assessed by magnetic resonance imaging–proton density …
Evaluation of drug–human serum albumin binding interactions with support vector machine aided online automated docking
F Zsila, Z Bikadi, D Malik, P Hari, I Pechan… - …, 2011 - academic.oup.com
Motivation: Human serum albumin (HSA), the most abundant plasma protein is well known
for its extraordinary binding capacity for both endogenous and exogenous substances, …
for its extraordinary binding capacity for both endogenous and exogenous substances, …
Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein
Human P-glycoprotein (P-gp) is an ATP-binding cassette multidrug transporter that confers
resistance to a wide range of chemotherapeutic agents in cancer cells by active efflux of the …
resistance to a wide range of chemotherapeutic agents in cancer cells by active efflux of the …
Low and high birth weights are risk factors for nonalcoholic fatty liver disease in children
…, S Buie, AM Diehl, C Guy, C Kigongo, D Malik… - The Journal of …, 2017 - Elsevier
Objectives To examine the distribution of birth weight in children with nonalcoholic fatty liver
disease (NAFLD) compared with the general US population, and to investigate the …
disease (NAFLD) compared with the general US population, and to investigate the …
Clinical and metabolic effects associated with weight changes and obeticholic acid in non‐alcoholic steatohepatitis
…, C Guy, C Kigongo, M Kopping, D Malik… - Alimentary …, 2018 - Wiley Online Library
Background In a 72‐week, randomised controlled trial of obeticholic acid ( OCA ) in non‐alcoholic
steatohepatitis ( NASH ), OCA was superior to placebo in improving serum ALT levels …
steatohepatitis ( NASH ), OCA was superior to placebo in improving serum ALT levels …
Rotational compound state resonances for an argon and methane scattering system
A broad compound state (closed channel) resonance in the argon-methane system is
investigated using a realistic model potential, and approximations are developed which allow one …
investigated using a realistic model potential, and approximations are developed which allow one …
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …
Ab initio determination of molecular electrical properties
CE Dykstra, S LIU, DJ Malik - Advances in Chemical Physics …, 2009 - books.google.com
Theoretical knowledge of molecular electrical moments and polarizabilities has reached an
important threshold. Methods have advanced considerably in the last several years and …
important threshold. Methods have advanced considerably in the last several years and …
[PDF][PDF] A pilot genome‐wide analysis study identifies loci associated with response to obeticholic acid in patients with NASH
…, C Guy, C Kigongo, M Kopping, D Malik… - Hepatology …, 2019 - Wiley Online Library
A significantly higher proportion of patients with nonalcoholic steatohepatitis (NASH) who
received obeticholic acid (OCA) had histological improvement relative to placebo in the FLINT (…
received obeticholic acid (OCA) had histological improvement relative to placebo in the FLINT (…