PURPOSE: To report outcomes of ophthalmic evaluations in clinical studies of patients receiving
fingolimod (Gilenya; Novartis Pharma AG, Basel, Switzerland) for multiple sclerosis (MS)…

Fingolimod treatment initiation is associated with a transient slowing of heart rate and
atrioventricular conduction. This report presents first-dose fingolimod effects (0.5 mg or 1.25 mg) …

Hierarchical modeling is wonderful and here to stay, but hyperparameter priors are often
chosen in a casual fashion. Unfortunately, as the number of hyperparameters grows, the effects …

Background and objective Face images often change in posture, Angle, expression, makeup,
aging, lighting, and other aspects. The performance of many models with high accuracy in …

The rapid advancement of single‐cell sequencing technology has generated extensive data,
providing critical resources for colorectal cancer (CRC) research. This study conducts a …

Background/Objectives: Biosimilar studies use overall response rate to assess clinical
similarity. Sample size and power depend on the equivalence margin, defined in either risk …

We consider the stochastic inviscid Leray- α model on the torus driven by transport noise.
Under a suitable scaling of the noise, we prove that the weak solutions converge, in some …

A typical biosimilar study in oncology uses the overall response evaluated at a specific time
point as the primary endpoint, which is generally acceptable regulatorily, to assess clinical …

Based on the first-principles study, the adsorption and electron transfer properties of Li atom
at different sites of SnS 2 monolayer, SnS 2 @Graphene 2D-nanocomposite are analyzed. …

Abstract: Aiming at the problems of mesh visual feature loss and oversimplification in mesh
simplification algorithm, a visual feature preservation based triangle mesh model …