Sarcopenia is an aged-related syndrome that is progressive and can be accelerated by
other concomitant disease states. Sarcopenia, characterized by loss of skeletal muscle mass, …

In contrast to non-mammalian vertebrates, mammals and humans have limited innate
capacity for the self-regeneration of tissues and organs owing to differences in genetics, …

In the paper, we review our work on heterogeneous III-V-on-silicon photonic components
and circuits for applications in optical communication and sensing. We elaborate on the …

Cytokines such as interleukin-6 induce tyrosine and serine phosphorylation of Stat3 that
results in activation of Stat3-responsive genes. We provide evidence that Stat3 is present in the …

Signal transducers and activators of transcription (STAT) proteins can be conditionally activated
in response to epidermal growth factor (EGF) and interferon (IFN)-γ. STAT activation was …

ISGF-3 is an interferon-dependent positive-acting transcription factor that is cytoplasmically
activated, possibly through direct interaction with the interferon receptor. The factor has been …

Protein tyrosine kinases activate the STAT (signal transducer and activator of transcription)
signaling pathway, which can play essential roles in cell differentiation, cell cycle control, and …

Interferon-stimulated gene factor 3 (ISGF3) is the ligand-dependent transcriptional activator
that, in response to interferon treatment, is assembled in the cell cytoplasm, is translocated to …

Aim: To investigate the status of Phosphatidylinositol 3‐kinase (PI3K)/PTEN/AKT/mammalian
target of rapamycin (mTOR) pathway and its correlation with clinicopathological features …

Signal transducer and activator of transcription 3 (STAT3) is a key transcriptional mediator for
many cytokines and is essential for normal embryonic development. We have generated a …