Untranslated regions of mRNAs

F Mignone, C Gissi, S Liuni, G Pesole - Genome biology, 2002 - Springer
Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated
regions of mRNAs that control their translation, degradation and localization include …

Structural and functional features of eukaryotic mRNA untranslated regions

G Pesole, F Mignone, C Gissi, G Grillo, F Licciulli… - Gene, 2001 - Elsevier
The crucial role of the non-coding portion of genomes is now widely acknowledged. In
particular, mRNA untranslated regions are involved in many post-transcriptional regulatory …

UTRdb and UTRsite (RELEASE 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs

G Grillo, A Turi, F Licciulli, F Mignone… - Nucleic acids …, 2010 - academic.oup.com
The 5′ and 3′ untranslated regions of eukaryotic mRNAs (UTRs) play crucial roles in the
post-transcriptional regulation of gene expression through the modulation of nucleo-…

UTRdb and UTRsite: specialized databases of sequences and functional elements of 5′ and 3′ untranslated regions of eukaryotic mRNAs. Update 2002

…, S Liuni, G Grillo, F Licciulli, F Mignone… - Nucleic acids …, 2002 - academic.oup.com
The 5′- and 3′-untranslated regions (5′- and 3′-UTRs) of eukaryotic mRNAs are
known to play a crucial role in post-transcriptional regulation of gene expression modulating …

uAUG and uORFs in human and rodent 5′ untranslated mRNAs

M Iacono, F Mignone, G Pesole - Gene, 2005 - Elsevier
The control of translation is a fundamental mechanism in the regulation of gene expression.
Among the cis-acting elements that play a role in translation regulation are upstream open …

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

…, M Askarian-Amiri, RJ Bonnal, M Callari, F Mignone… - BMC genomics, 2009 - Springer
Background The cancer transcriptome is difficult to explore due to the heterogeneity of
quantitative and qualitative changes in gene expression linked to the disease status. An …

UTRdb and UTRsite: a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs

F Mignone, G Grillo, F Licciulli, M Iacono… - Nucleic acids …, 2005 - academic.oup.com
The 5′ and 3′ untranslated regions of eukaryotic mRNAs play crucial roles in the post-transcriptional
regulation of gene expression through the modulation of nucleo-cytoplasmic …

Discrimination of non-protein-coding transcripts from protein-coding mRNA

MC Frith, TL Bailey, T Kasukawa, F Mignone… - RNA biology, 2006 - Taylor & Francis
Several recent studies indicate that mammals and other organisms produce large numbers
of RNA transcripts that do not correspond to known genes. It has been suggested that these …

Gene Expression Rhythms in the Mussel Mytilus galloprovincialis (Lam.) across an Annual Cycle

M Banni, A Negri, F Mignone, H Boussetta… - PLoS …, 2011 - journals.plos.org
Seasonal environmental changes may affect the physiology of Mytilus galloprovincialis (Lam.),
an intertidal filter-feeder bivalve occurring commonly in Mediterranean and Atlantic …

Prospective assessment of NGS-detectable mutations in CML patients with nonoptimal response: the NEXT-in-CML study

…, G Saglio, F Pane, P Vigneri, F Mignone… - Blood, The Journal …, 2020 - ashpublications.org
In chronic myeloid leukemia (CML) patients, tyrosine kinase inhibitors (TKIs) may select for
drug-resistant BCR-ABL1 kinase domain (KD) mutants. Although Sanger sequencing (SS) is …