User profiles for Gene Tan
Gene S. TanJ. Craig Venter Institute Verified email at jcvi.org Cited by 9211 |
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19 (PASC).
Several biological factors have emerged as potential drivers of PASC pathology. Some …
Several biological factors have emerged as potential drivers of PASC pathology. Some …
[HTML][HTML] SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?
The ongoing SARS-CoV-2 pandemic has led to the focused application of resources and
scientific expertise toward the goal of developing investigational vaccines to prevent COVID-19…
scientific expertise toward the goal of developing investigational vaccines to prevent COVID-19…
Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR
The National Institute of Allergy and Infectious Diseases (NIAID) established the Bioinformatics
Resource Center (BRC) program to assist researchers with analyzing the growing body …
Resource Center (BRC) program to assist researchers with analyzing the growing body …
Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo
Neutralizing antibodies against influenza viruses have traditionally been thought to provide
protection exclusively through their variable region; the contributions of mechanisms …
protection exclusively through their variable region; the contributions of mechanisms …
Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes
Current influenza virus vaccines protect mostly against homologous virus strains; thus, regular
immunization with updated vaccine formulations is necessary to guard against the virus' …
immunization with updated vaccine formulations is necessary to guard against the virus' …
Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins
As targets of adaptive immunity, influenza viruses are characterized by the fluidity with which
they respond to the selective pressure applied by neutralizing antibodies. This mutability of …
they respond to the selective pressure applied by neutralizing antibodies. This mutability of …
Proinflammatory IgG Fc structures in patients with severe COVID-19
…, T Morales, JM Schapiro, GS Tan… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 infections can cause coronavirus disease
2019 (COVID-19), which manifests with a range of severities from mild illness to life-…
2019 (COVID-19), which manifests with a range of severities from mild illness to life-…
Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes
The influenza virus hemagglutinin molecule possesses a globular head domain that mediates
receptor binding and a stalk domain at the membrane-proximal region. We generated …
receptor binding and a stalk domain at the membrane-proximal region. We generated …
Both neutralizing and non-neutralizing human H7N9 influenza vaccine-induced monoclonal antibodies confer protection
…, M Huang, A Choi, V Chromikova, IY Ho, GS Tan… - Cell host & …, 2016 - cell.com
Pathogenic H7N9 avian influenza viruses continue to represent a public health concern, and
several candidate vaccines are currently being developed. It is vital to assess if protective …
several candidate vaccines are currently being developed. It is vital to assess if protective …
Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses
After the emergence of pandemic influenza viruses in 1957, 1968, and 2009, existing seasonal
viruses were observed to be replaced in the human population by the novel pandemic …
viruses were observed to be replaced in the human population by the novel pandemic …