Metabolic regulation of gene expression by histone lactylation
The Warburg effect, which originally described increased production of lactate in cancer, is
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …
Construction of a human cell landscape at single-cell level
Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems
1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here …
1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here …
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
Signalling by the Wnt family of secreted lipoproteins has essential functions in development
and disease 1 . The canonical Wnt/β-catenin pathway requires a single-span …
and disease 1 . The canonical Wnt/β-catenin pathway requires a single-span …
[HTML][HTML] Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China
…, J Zhang, X Wu, W Chen, CL Dennis, H Huang - American journal of …, 2020 - Elsevier
Background On January 20, 2020, a new coronavirus epidemic with human-to-human
transmission was officially declared by the Chinese government, which caused significant public …
transmission was officially declared by the Chinese government, which caused significant public …
Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China
…, J Liang, Q Zhao, H Huang, B Yang, C Huang - JAMA …, 2020 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity
and mortality worldwide since December 2019. However, information on cardiac injury in …
and mortality worldwide since December 2019. However, information on cardiac injury in …
Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL
Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating
haematological malignancies 1 , 2 , 3 , 4 , 5 , 6 – 7 . However, CAR-T cell therapy currently …
haematological malignancies 1 , 2 , 3 , 4 , 5 , 6 – 7 . However, CAR-T cell therapy currently …
[HTML][HTML] FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
Wnt/β-catenin signaling is essential for stem cell regulation and tumorigenesis, but its
molecular mechanisms are not fully understood. Here, we report that FoxM1 is a downstream …
molecular mechanisms are not fully understood. Here, we report that FoxM1 is a downstream …
Strong quantum computational advantage using a superconducting quantum processor
Scaling up to a large number of qubits with high-precision control is essential in the
demonstrations of quantum computational advantage to exponentially outpace the classical …
demonstrations of quantum computational advantage to exponentially outpace the classical …
Inflammation and aging: signaling pathways and intervention therapies
Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019
…, Q Zhao, H Huang, B Yang, C Huang - European heart …, 2020 - academic.oup.com
Aims To investigate the characteristics and clinical significance of myocardial injury in patients
with severe coronavirus disease 2019 (COVID-19). Methods and results We enrolled 671 …
with severe coronavirus disease 2019 (COVID-19). Methods and results We enrolled 671 …