User profiles for Heng Mei

Heng Mei

Harbin Institute of Technology
Verified email at u.nus.edu
Cited by 40

Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial

…, S Zheng, J Yang, Y Kong, L Ren, Q Wei, H Mei… - Jama, 2020 - jamanetwork.com
Importance Convalescent plasma is a potential therapeutic option for patients with coronavirus
disease 2019 (COVID-19), but further data from randomized clinical trials are needed. …

Deep vein thrombosis in hospitalized patients with COVID-19 in Wuhan, China: prevalence, risk factors, and outcome

L Zhang, X Feng, D Zhang, C Jiang, H Mei, J Wang… - Circulation, 2020 - ahajournals.org
Background: To investigate deep vein thrombosis (DVT) in hospitalized patients with
coronavirus disease 2019 (COVID-19), we performed a single institutional study to evaluate its …

[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification

H Mei, S Cai, D Huang, H Gao, J Cao, B He - Bioactive materials, 2022 - Elsevier
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

A bispecific CAR-T cell therapy targeting BCMA and CD38 in relapsed or refractory multiple myeloma

H Mei, C Li, H Jiang, X Zhao, Z Huang, D Jin… - Journal of hematology & …, 2021 - Springer
Background BCMA-specific chimeric antigen receptor-T cells (CAR-Ts) have exhibited
remarkable efficacy in refractory or relapsed multiple myeloma (RRMM); however, primary …

Applications and explorations of CRISPR/Cas9 in CAR T-cell therapy

C Li, H Mei, Y Hu - Briefings in functional genomics, 2020 - academic.oup.com
Chimeric antigen receptor(CAR) T-cell therapy has shown remarkable effects and promising
prospects in patients with refractory or relapsed malignancies, pending further progress in …

Fluorocarbon-driven photosensitizer assembly decodes energy conversion pathway for suppressing breast tumor

H Mei, X Zhang, S Cai, X Zhang, Y Zhang, Z Guo… - Nano Today, 2021 - Elsevier
Despite enlarging the clinical applicability of organic photosensitizers in photodynamic
therapy (PDT), current nanoencapsulation technology prefers to improve photothermal …

Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study

…, P Yin, Y Wang, L Tang, J Deng, H Mei… - The Lancet …, 2020 - thelancet.com
Background COVID-19 is an ongoing global pandemic. Changes in haematological
characteristics in patients with COVID-19 are emerging as important features of the disease. We …

Evaluation the combined diagnostic value of TAT, PIC, tPAIC, and sTM in disseminated intravascular coagulation: a multi-center prospective observational study

H Mei, Y Jiang, L Luo, R Huang, L Su, M Hou… - Thrombosis research, 2019 - Elsevier
Background Accurate and early diagnosis is important in the management of disseminated
intravascular coagulation (DIC). We employed new automation technology to detect plasma …

Quasi-static experimental study on seismic performance of exterior shear key with different failure modes

H Mei, A Guo - Engineering Structures, 2023 - Elsevier
The shear key with horizontal failure mode manifests secondary stiffness-strengthening
capacity comparing to the diagonal and slide shear modes. It is more suitable for protecting …

Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)

P Lertkiatmongkol, D Liao, H Mei, Y Hu… - Current opinion in …, 2016 - journals.lww.com
Owing to the unique ability of antibodies that bind the membrane proximal region of the
extracellular domain to trigger conformational changes leading to affinity modulation and …