A program to construct ensembles of biomolecular structures that are consistent with experimental
scattering data are described. Specifically, we generate an ensemble of biomolecular …

The retroviral Gag polyprotein mediates viral assembly. The Gag protein has been shown to
interact with other Gag proteins, with the viral RNA, and with the cell membrane during the …

Mixed self-assembled monolayers (SAMs) of β-mercaptoethanol and the new synthetic lipid
1,2-dipalmityl-3-[ω-mercaptonona(ethylene oxide)] glycerol (FC16) were investigated for …

The association between monovalent salts and neutral lipid bilayers is known to influence
global bilayer structural properties such as headgroup conformational fluctuations and the …

Biological membranes are composed of a thermally disordered lipid matrix and therefore
require non-crystallographic scattering approaches for structural characterization with x-rays or …

Adsorption of proteins to solid-fluid interfaces is often empirically found to promote formation
of soluble aggregates and larger, subvisible, and visible particles, but key stages in this …

The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize
best practices, share experiences, and generate innovative methodologies to facilitate …

The N-terminal matrix (MA) domain of the HIV-1 Gag protein is responsible for binding to the
plasma membrane of host cells during viral assembly. The putative membrane-binding …

Single-chain fragment variable (scFv) domains play an important role in antibody-based
therapeutic modalities, such as bispecifics, multispecifics and chimeric antigen receptor T cells …

The structure, interactions, and interprotein configurations of the protein lysozyme were
studied in a variety of phases. These properties have been studied under a variety of solution …