As an excellent fluorescent nanomaterial, carbon quantum dots (CQDs) have the properties
of small molecular weight, small particle size, high fluorescence stability, no optical flicker, …

China faces the greatest challenge from stroke in the world. The death rate for cerebrovascular
diseases in China was 149.49 per 100 000, accounting for 1.57 million deaths in 2018. It …

Missing values and dropouts are common issues in longitudinal studies in all areas of medicine
and public health. Intent-to-treat (ITT) analysis has become a widely accepted method …

The Cre/lox system is widely used in mice to achieve cell-type-specific gene expression.
However, a strong and universally responding system to express genes under Cre control is still …

Monodisperse magnetite nanoparticles provide a more factual model to study the interface
interactions between the surfactants and magnetic nanoparticles. Monodisperse magnetite …

Cell type–specific expression of optogenetic molecules allows temporally precise manipulation
of targeted neuronal activity. Here we present a toolbox of four knock-in mouse lines …

An increasingly powerful approach for studying brain circuits relies on targeting genetically
encoded sensors and effectors to specific cell types. However, current approaches for this …

Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread
throughout the world, resulting in a global public health emergency. The lack of vaccine and …

Background Alteplase is the standard agent used in early reperfusion therapy, but alternative
thrombolytic agents are needed. The efficacy and safety of reteplase as compared with …

Modern genetic approaches are powerful in providing access to diverse cell types in the brain
and facilitating the study of their function. Here, we report a large set of driver and reporter …