α-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

J Yaung, M Jin, E Barron, C Spee… - Molecular …, 2007 - pmc.ncbi.nlm.nih.gov
Purpose To investigate the susceptibility of retinal pigment epithelium (RPE) from αA (-/-) and
αB (-/-) mice to oxidative stress, and the subcellular changes of αA and αB-crystallins under …

Intel 4 CMOS technology featuring advanced FinFET transistors optimized for high density and high-performance computing

…, J Wnuk, SQ Xu, P Yashar, J Yaung… - … IEEE Symposium on …, 2022 - ieeexplore.ieee.org
A new advanced CMOS FinFET technology, Intel 4, is introduced that extends Moore’s law
by offering 2X area scaling of the high performance logic library and greater than 20% …

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

J Yaung, R Kannan, EF Wawrousek, C Spee… - Experimental eye …, 2008 - Elsevier
This study evaluated the role of crystallins in retinal degeneration induced by chemical hypoxia.
Wild-type, αA-crystallin (−/−), and αB-crystallin (−/−) mice received intravitreal injection of …

Characterization of contact resistance stability in MEM relays with tungsten electrodes

Y Chen, R Nathanael, J Jeon, J Yaung… - Journal of …, 2012 - ieeexplore.ieee.org
The impact of device operating parameters on the ON-state resistance (R ON ) of
microelectromechanical relays with tungsten (W) electrodes is reported. Due to the susceptibility of W …

Adhesive force characterization for MEM logic relays with sub-micron contacting regions

J Yaung, L Hutin, J Jeon, TJK Liu - Journal of …, 2013 - ieeexplore.ieee.org
… The Hamaker constant for tungsten is 40 × 10 −20 J [11]. In order to adapt this model to the
… Jack Yaung received the BS degree in electrophysics from National Chiao Tung University, …

Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells

S He, J Yaung, YH Kim, E Barron, SJ Ryan… - Graefe's Archive for …, 2008 - Springer
Background Induction of glucose-regulated protein (GRP)-78 in the endoplasmic reticulum (ER)
is a protective mechanism cells use to adapt to ER stress. We evaluated the expression …

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

KM Esvelt, P Mali, JL Braff, M Moosburner, SJ Yaung… - Nature …, 2013 - nature.com
The Cas9 protein from the Streptococcus pyogenes CRISPR-Cas acquired immune system
has been adapted for both RNA-guided genome editing and gene regulation in a variety of …

Protection from oxidative stress by methionine sulfoxide reductases in RPE cells

PG Sreekumar, R Kannan, J Yaung, CK Spee… - Biochemical and …, 2005 - Elsevier
We investigated the role of methionine sulfoxide reductases (Msrs) in oxidant-stress-induced
cell death in retinal pigmented epithelial (RPE) cells. In RPE cells exposed to varying …

Current practices in nutrition therapy in cardiac surgery patients: An international multicenter observational study

…, V Lomivorotov, C Compher, J Yaung… - Journal of Parenteral …, 2023 - Wiley Online Library
Background Cardiac surgery patients with a prolonged stay in the intensive care unit (ICU)
are at high risk for acquired malnutrition. Medical nutrition therapy practices for cardiac …

[HTML][HTML] Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion

ML Jin, J Yaung, R Kannan, S He, SJ Ryan… - … & visual science, 2005 - arvojournals.org
purpose. To study the mechanism of the protective effect of hepatocyte growth factor (HGF)
in oxidative injury to RPE cells induced by glutathione (GSH) depletion. methods. RPE cells …