FOXP3 exon 2 controls Treg stability and autoimmunity

…, M Haouili, S Liu, J Wan, L Han, J Liu… - Science …, 2022 - science.org
Differing from the mouse Foxp3 gene that encodes only one protein product, human FOXP3
encodes two major isoforms through alternative splicing—a longer isoform (FOXP3 FL) …

GESS: a database of global evaluation of SARS-CoV-2/hCoV-19 sequences

S Fang, K Li, J Shen, S Liu, J Liu, L Yang… - Nucleic acids …, 2021 - academic.oup.com
The COVID-19 outbreak has become a global emergency since December 2019. Analysis
of SARS-CoV-2 sequences can uncover single nucleotide variants (SNVs) and …

Genetic spectrum and distinct evolution patterns of SARS-CoV-2

S Liu, J Shen, S Fang, K Li, J Liu, L Yang… - Frontiers in …, 2020 - frontiersin.org
Four signature groups of frequently occurred single-nucleotide variants (SNVs) were identified
in over twenty-eight thousand high-quality and high-coverage SARS-CoV-2 complete …

Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes

S Chen, J Liu, X Liu, Y Fu, M Zhang, Q Lin, J Zhu… - Journal of …, 2011 - Elsevier
AIM OF THIS STUDY: The panax notoginseng saponins (PNS) have been clinically used for
the treatment of cardiovascular diseases and stroke in China. Evidences demonstrated that …

Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells

J Liu, S Liu, H Gao, L Han, X Chu, Y Sheng, W Shou… - Genome biology, 2020 - Springer
Background Early human heart and brain development simultaneously occur during
embryogenesis. Notably, in human newborns, congenital heart defects strongly associate with …

LncRNA HBL1 is required for genome-wide PRC2 occupancy and function in cardiogenesis from human pluripotent stem cells

J Liu, S Liu, L Han, Y Sheng, Y Zhang, IM Kim… - …, 2021 - journals.biologists.com
Polycomb repressive complex 2 (PRC2) deposits H3K27me3 on chromatin to silence transcription.
PRC2 broadly interacts with RNAs. Currently, the role of the RNA-PRC2 interaction in …

HBL1 is a human long noncoding RNA that modulates cardiomyocyte development from pluripotent stem cells by counteracting MIR1

J Liu, Y Li, B Lin, Y Sheng, L Yang - Developmental cell, 2017 - cell.com
Cardiogenesis processes in human and animals have differential dynamics, suggesting the
existence of species-specific regulators during heart development. However, it remains a …

Muscle LIM protein force-sensing mediates sarcomeric biomechanical signaling in human familial hypertrophic cardiomyopathy

…, PT Pomianowski, Y Huang, MW Ellis, J Luo, J Liu… - Circulation, 2022 - ahajournals.org
Background: Familial hypertrophic cardiomyopathy (HCM) is the most common inherited
cardiac disease and is typically caused by mutations in genes encoding sarcomeric proteins …

Determination of capsaicin and dihydrocapsaicin in Capsicum anuum and related products by capillary electrophoresis with a mixed surfactant system

L Liu, X Chen, J Liu, X Deng, W Duan, S Tan - Food Chemistry, 2010 - Elsevier
An easy, rapid, sensitive, and cheap capillary electrophoresis (CE) method based a mixed
surfactant system formed by sodium dodecyl sulphate (SDS) and polyoxyethylene sorbitan …

[HTML][HTML] Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse

…, X Deng, B Liu, Y Zhang, Q Fu, X Huang, J Liu… - Bioactive materials, 2024 - Elsevier
Abdominal Aortic Aneurysm (AAA) is a life-threatening vascular disease characterized by
the weakening and ballooning of the abdominal aorta, which has no effective therapeutic …