User profiles for Jumpei Ito
Jumpei ItoDivision of Systems Virology, Institute of Medical Science, The University of Tokyo Verified email at g.ecc.u-tokyo.ac.jp Cited by 5448 |
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern 1
. In this study, our statistical modelling suggests that Omicron has spread more rapidly than …
. In this study, our statistical modelling suggests that Omicron has spread more rapidly than …
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation
During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (…
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (…
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ. 1.1 variant
In late 2022, various Omicron subvariants emerged and cocirculated worldwide. These
variants convergently acquired amino acid substitutions at critical residues in the spike protein, …
variants convergently acquired amino acid substitutions at critical residues in the spike protein, …
Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is
spreading rapidly around the world. Our phylogenetic analyses suggested that XBB …
spreading rapidly around the world. Our phylogenetic analyses suggested that XBB …
[HTML][HTML] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
…, I Kimura, K Uriu, Y Kosugi, Y Yue, R Shimizu, J Ito… - Cell host & …, 2021 - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …
mutations can affect viral properties such as infectivity and immune resistance. Although the …
[HTML][HTML] Virological characteristics of the SARS-CoV-2 Omicron BA. 2 spike
Soon after the emergence and global spread of the SARS-CoV-2 Omicron lineage BA.1,
another Omicron lineage, BA.2, began outcompeting BA.1. The results of statistical analysis …
another Omicron lineage, BA.2, began outcompeting BA.1. The results of statistical analysis …
Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5
After the global spread of the SARS-CoV-2 Omicron BA.2, some BA.2 subvariants, including
BA.2.9.1, BA.2.11, BA.2.12.1, BA.4, and BA.5, emerged in multiple countries. Our statistical …
BA.2.9.1, BA.2.11, BA.2.12.1, BA.4, and BA.5, emerged in multiple countries. Our statistical …
Crystal structure of the channelrhodopsin light-gated cation channel
…, C Ramakrishnan, T Nishizawa, K Hirata, J Ito… - Nature, 2012 - nature.com
Channelrhodopsins (ChRs) are light-gated cation channels derived from algae that have
shown experimental utility in optogenetics; for example, neurons expressing ChRs can be …
shown experimental utility in optogenetics; for example, neurons expressing ChRs can be …
Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies
2 Kimura I, Kosugi Y, Wu J, et al. The SARS-CoV-2 lambda variant exhibits enhanced infectivity
and immune resistance. Cell Rep 2022; 38: 110218. 3 Bruel T, Hadjadj J, Maes P, et al. …
and immune resistance. Cell Rep 2022; 38: 110218. 3 Bruel T, Hadjadj J, Maes P, et al. …
Virological characteristics of the SARS-CoV-2 JN. 1 variant
… 7 Uriu K, Ito J, Zahradnik J, et al. Enhanced transmissibility, infectivity, and immune
resistance of the SARS-CoV-2 omicron XBB.1.5 variant. Lancet Infect Dis 2023; 23: 280–81. …
resistance of the SARS-CoV-2 omicron XBB.1.5 variant. Lancet Infect Dis 2023; 23: 280–81. …