MicroRNAs (miRNAs) are a class of short, endogenously-initiated non-coding RNAs that
post-transcriptionally control gene expression via either translational repression or mRNA …

Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of
CRC is its intimate association with the gut microbiota, which forms an essential part of the …

Pretrained Foundation Models (PFMs) are regarded as the foundation for various downstream
tasks across different data modalities. A PFM (eg, BERT, ChatGPT, GPT-4) is trained on …

We have produced a draft sequence of the rice genome for the most widely cultivated
subspecies in China, Oryza sativa L. ssp.indica, by whole-genome shotgun sequencing. The …

We report improved whole-genome shotgun sequences for the genomes of indica and
japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the …

KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous
(Ks) substitution rates through model selection and model averaging. Since existing …

We report a draft sequence for the genome of the domesticated silkworm (Bombyx mori),
covering 90.9% of all known silkworm genes. Our estimated gene count is 18,510, which …

Objective To evaluate the potential for diagnosing colorectal cancer (CRC) from faecal
metagenomes. Design We performed metagenome-wide association studies on faecal samples …

Bacterial pathogens continue to impose a major threat to public health worldwide in the 21st
century. Intensified studies on bacterial pathogenesis have greatly expanded our …

We established a catalog of the mouse gut metagenome comprising ∼2.6 million nonredundant
genes by sequencing DNA from fecal samples of 184 mice. To secure high microbiome …