Compact cardiomyocytes that make up the ventricular wall of the adult heart represent an
important therapeutic target population for modeling and treating cardiovascular diseases. …

Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we
used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF …

Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds
a promise to revolutionize drug discovery, but only if limitations related to cardiac chamber …

The ability to direct the differentiation of human pluripotent stem cells (hPSCs) to the different
cardiomyocyte subtypes is a prerequisite for modeling specific forms of cardiovascular …

To unravel the roles of LXRs in inflammation and immunity, we examined the function of
LXRs in development of IFN-γ-mediated inflammation using cultured rat brain astrocytes. LXR …

A 70% ethanol extract from the root portion of Reynoutria japonica afforded one new and
three known juglone derivatives, namely, 2-methoxy-6-acetyl-7-methyljuglone (1), 2-ethoxy-6-…

Advances in our understanding of cardiovascular development have provided a roadmap for
the directed differentiation of human pluripotent stem cells (hPSCs) to the major cell types …

Gangliosides participate in various cellular events of the central nervous system and have
been closely implicated in many neuronal diseases. However, the precise molecular …

Accumulating evidence indicates that endoplasmic reticulum (ER) stress is a common
feature of Parkinson’s disease (PD) and further suggests that several PD-related genes are …

New ideas are often born from connecting the dots. What new ideas have emerged among
the two highly trending research topics of sustainability and social media? In this study, we …