Cytotoxicity of Human pI 7 Interleukin-1 for Pancreatic Islets of Langerhans
K Bendtzen, T Mandrup-Poulsen, J Nerup, JH Nielsen… - Science, 1986 - science.org
Activated mononuclear cells appear to be important effector cells in autoimmune beta cell
destruction leading to insulin-dependent (type 1) diabetes mellitus. Conditioned medium from …
destruction leading to insulin-dependent (type 1) diabetes mellitus. Conditioned medium from …
Laser-induced alignment and orientation of quantum-state-selected large molecules
L Holmegaard, JH Nielsen, I Nevo, H Stapelfeldt… - Physical review …, 2009 - APS
A strong inhomogeneous static electric field is used to spatially disperse a supersonic beam
of polar molecules, according to their quantum state. We show that the molecules residing in …
of polar molecules, according to their quantum state. We show that the molecules residing in …
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
…, K Lindberg, DJ Hilton, JH Nielsen… - Molecular …, 1999 - academic.oup.com
In this study we have investigated the role of suppressor of cytokine signaling (SOCS) proteins
in GH receptor-mediated signaling. GH-induced transcription was inhibited by SOCS-1 …
in GH receptor-mediated signaling. GH-induced transcription was inhibited by SOCS-1 …
abYsis: integrated antibody sequence and structure—management, analysis, and prediction
abYsis is a web-based antibody research system that includes an integrated database of
antibody sequence and structure data. The system can be interrogated in numerous ways—…
antibody sequence and structure data. The system can be interrogated in numerous ways—…
Quantum-state selection, alignment, and orientation of large molecules using static electric and laser fields
…, JH Nielsen, I Nevo, JL Hansen, H Stapelfeldt - The Journal of …, 2009 - pubs.aip.org
Supersonic beams of polar molecules are deflected using inhomogeneous electric fields.
The quantum-state selectivity of the deflection is used to spatially separate molecules …
The quantum-state selectivity of the deflection is used to spatially separate molecules …
Stimulation of pancreatic β-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways
…, N Blume, JS Petersen, JH Nielsen… - Journal of …, 2006 - joe.bioscientifica.com
… Jens H Nielsen Jens H Nielsen … Jens H Nielsen was supported by The Juvenile Diabetes
Research Foundation, Danish Center for Stem Cell Research (Danish Medical Research …
Research Foundation, Danish Center for Stem Cell Research (Danish Medical Research …
MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion
…, L Larsen, O Vang, JH Nielsen… - Biochemical and …, 2012 - Elsevier
Chronically elevated levels of glucose impair pancreatic beta-cell function while inducing
beta-cell proliferation. MicroRNA-29a (miR-29a) levels are increased in several tissues in …
beta-cell proliferation. MicroRNA-29a (miR-29a) levels are increased in several tissues in …
Impact of fetal and neonatal environment on beta cell function and development of diabetes
JH Nielsen, TN Haase, C Jaksch… - Acta obstetricia et …, 2014 - Wiley Online Library
The global epidemic of diabetes is a serious threat against health and healthcare expenses.
Although genetics is important it does not explain the dramatic increase in incidence, which …
Although genetics is important it does not explain the dramatic increase in incidence, which …
Suppressor of cytokine signaling 3 (SOCS-3) protects β-cells against interleukin-1β-and interferon-γ-mediated toxicity
…, ED Galsgaard, F Pociot, JH Nielsen… - Proceedings of the …, 2001 - National Acad Sciences
Suppressor of cytokine signaling 3 (SOCS-3) is a negative feedback regulator of IFN-γ
signaling, shown up-regulated in mouse bone marrow cells by the proinflammatory cytokines …
signaling, shown up-regulated in mouse bone marrow cells by the proinflammatory cytokines …
Laser-induced 3D alignment and orientation of quantum state-selected molecules
…, JH Nielsen, JL Hansen, H Stapelfeldt… - Physical Chemistry …, 2009 - pubs.rsc.org
A strong inhomogeneous static electric field is used to spatially disperse a rotationally cold
supersonic beam of 2,6-difluoroiodobenzene molecules according to their rotational quantum …
supersonic beam of 2,6-difluoroiodobenzene molecules according to their rotational quantum …