Gebruikersprofielen voor Jens H. Nielsen

Jens H. Nielsen

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Jens Høiriis Nielsen

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Cytotoxicity of Human pI 7 Interleukin-1 for Pancreatic Islets of Langerhans

K Bendtzen, T Mandrup-Poulsen, J Nerup, JH Nielsen… - Science, 1986 - science.org
Activated mononuclear cells appear to be important effector cells in autoimmune beta cell
destruction leading to insulin-dependent (type 1) diabetes mellitus. Conditioned medium from …

Laser-induced alignment and orientation of quantum-state-selected large molecules

L Holmegaard, JH Nielsen, I Nevo, H Stapelfeldt… - Physical review …, 2009 - APS
A strong inhomogeneous static electric field is used to spatially disperse a supersonic beam
of polar molecules, according to their quantum state. We show that the molecules residing in …

Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins

…, K Lindberg, DJ Hilton, JH Nielsen… - Molecular …, 1999 - academic.oup.com
In this study we have investigated the role of suppressor of cytokine signaling (SOCS) proteins
in GH receptor-mediated signaling. GH-induced transcription was inhibited by SOCS-1 …

abYsis: integrated antibody sequence and structure—management, analysis, and prediction

…, M Couch, J Hurst, KR Abhinandan, JH Nielsen… - Journal of molecular …, 2017 - Elsevier
abYsis is a web-based antibody research system that includes an integrated database of
antibody sequence and structure data. The system can be interrogated in numerous ways—…

Quantum-state selection, alignment, and orientation of large molecules using static electric and laser fields

…, JH Nielsen, I Nevo, JL Hansen, H Stapelfeldt - The Journal of …, 2009 - pubs.aip.org
Supersonic beams of polar molecules are deflected using inhomogeneous electric fields.
The quantum-state selectivity of the deflection is used to spatially separate molecules …

Stimulation of pancreatic β-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways

…, N Blume, JS Petersen, JH Nielsen… - Journal of …, 2006 - joe.bioscientifica.com
Jens H Nielsen Jens H NielsenJens H Nielsen was supported by The Juvenile Diabetes
Research Foundation, Danish Center for Stem Cell Research (Danish Medical Research …

MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion

…, L Larsen, O Vang, JH Nielsen… - Biochemical and …, 2012 - Elsevier
Chronically elevated levels of glucose impair pancreatic beta-cell function while inducing
beta-cell proliferation. MicroRNA-29a (miR-29a) levels are increased in several tissues in …

Impact of fetal and neonatal environment on beta cell function and development of diabetes

JH Nielsen, TN Haase, C Jaksch… - Acta obstetricia et …, 2014 - Wiley Online Library
The global epidemic of diabetes is a serious threat against health and healthcare expenses.
Although genetics is important it does not explain the dramatic increase in incidence, which …

Suppressor of cytokine signaling 3 (SOCS-3) protects β-cells against interleukin-1β-and interferon-γ-mediated toxicity

…, ED Galsgaard, F Pociot, JH Nielsen… - Proceedings of the …, 2001 - National Acad Sciences
Suppressor of cytokine signaling 3 (SOCS-3) is a negative feedback regulator of IFN-γ
signaling, shown up-regulated in mouse bone marrow cells by the proinflammatory cytokines …

Laser-induced 3D alignment and orientation of quantum state-selected molecules

…, JH Nielsen, JL Hansen, H Stapelfeldt… - Physical Chemistry …, 2009 - pubs.rsc.org
A strong inhomogeneous static electric field is used to spatially disperse a rotationally cold
supersonic beam of 2,6-difluoroiodobenzene molecules according to their rotational quantum …