Enzymes are increasingly explored for use in asymmetric synthesis 1 , 2 – 3 , but their
applications are generally limited by the reactions available to naturally occurring enzymes. …

Multicomponent reactions—those where three or more substrates combine into a product—have
been highly useful in rapidly building chemical building blocks of increased complexity …

State-of-the-art non-natural photoenzymatic catalysis typically relies on either ultraviolet
light activation or the formation of electron donor–acceptor complexes. Inspired by nature, …

Since the discovery of Hofmann–Löffler–Freytag reaction more than 130 years ago, both the
structure and reactivity of nitrogen-centred radicals have been widely studied. Nevertheless, …

Exploiting nature’s catalysts for non-natural transformations that are inaccessible to
chemocatalysis is highly desirable but challenging. On the one hand, the widespread nicotinamide-…

The development of catalysts serves as the cornerstone of innovation in synthesis, as
exemplified by the recent discovery of photoenzymes. However, the repertoire of naturally …

Hydrogen sulfide (H 2 S) has been shown to protect against oxidative stress injury and
inflammation in various hypoxia-induced insult models. However, it remains unknown whether H …

Hydrogen sulfide (H 2 S) has been proposed as a novel neuromodulator and neuroprotective
agent. Cobalt chloride (CoCl 2 ) is a well-known hypoxia mimetic agent. We have …

We study the effect of applying metamorphic testing to alleviate the oracle problem for
numerical programs. We discuss a case study on the testing of a program that solves an elliptic …

Background/Aim: We have demonstrated that exogenous hydrogen sulfide (H 2 S) protects
H9c2 cardiac cells against the doxorubicin (DOX)-induced injuries by inhibiting p38 mitogen-…