MicroRNAs (miRNAs) can efficiently regulate gene expression by targeting mRNA to cause
mRNA cleavage or translational repression. Growing evidence indicates that miRNAs exist …

The preventive treatment of latent tuberculosis infection (LTBI) is of great importance for the
elimination and control of tuberculosis (TB) worldwide, but existing screening methods for …

Preventing aggregation of amyloid beta (Aβ) peptides is a promising strategy for the treatment
of Alzheimer’s disease (AD), and gold nanoparticles have previously been explored as a …

A microporous Cu-MOF with optimized open metal sites and pore space was constructed
based on a designed bent ligand; it exhibits high-capacity multiple gas storage under …

Objective. Tumor necrosis factor-α (TNF-α) antagonists have significantly improved treatment
results in rheumatoid arthritis (RA), but have also increased the risk of tuberculosis (TB). …

Recent studies have revealed the role of microRNAs (miRNAs) in a variety of basic biological
and pathological processes and the association of miRNA signatures with human diseases…

Background Expression of the polymeric immunoglobulin receptor (pIgR), a transporter of
polymeric IgA and IgM, is commonly increased in response to viral or bacterial infections, …

We study a novel “coverage by directional sensors” problem with tunable orientations on a
set of discrete targets. We propose a Maximum Coverage with Minimum Sensors (MCMS) …

Previous studies have demonstrated that chronic brain hypoperfusion (CBH) causes Aβ
aggregation by upregulating expression of amyloid precursor protein (APP) and β-site APP …

Rapid and simple-to-use diagnostic methods for tuberculosis are urgently needed. Recent
development has unveiled the diagnostic power of the CRISPR system in the detection of …