User profiles for Kyu Rhee

Kyu-Nam Rhee

Professor, Pukyong National University
Verified email at pknu.ac.kr
Cited by 1555

Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates

…, SM Fischer, J Marrero, C Nathan, S Ehrt, KY Rhee - Chemistry & biology, 2010 - cell.com
Metabolic adaptation to the host environment is a defining feature of the pathogenicity of
Mycobacterium tuberculosis (Mtb), but we lack biochemical knowledge of its metabolic networks…

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

K Pethe, PC Sequeira, S Agarwalla, K Rhee… - Nature …, 2010 - nature.com
Candidate antibacterials are usually identified on the basis of their in vitro activity. However,
the apparent inhibitory activity of new leads can be misleading because most culture media …

Para-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis

…, T Gruber, CE Barry III, HI Boshoff, KY Rhee - Science, 2013 - science.org
Folate biosynthesis is an established anti-infective target, and the antifolate para-aminosalicylic
acid (PAS) was one of the first anti-infectives introduced into clinical practice on the …

A 50 year review of basic and applied research in radiant heating and cooling systems for the built environment

KN Rhee, KW Kim - Building and Environment, 2015 - Elsevier
The radiant heating and cooling (RHC) system has been gaining much popularity due to high
thermal comfort, reduced energy consumption, quiet operation, space saving, and so on. …

Ten questions about radiant heating and cooling systems

KN Rhee, BW Olesen, KW Kim - Building and Environment, 2017 - Elsevier
Radiant heating and cooling (RHC) systems are being increasingly applied not only in residential
but also in non-residential buildings such as commercial buildings, education facilities, …

Precision medicine, AI, and the future of personalized health care

…, ME Frisse, K Misulis, K Rhee… - Clinical and …, 2021 - Wiley Online Library
The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize
health care. Precision medicine methods identify phenotypes of patients with less‐…

Dietary fructose improves intestinal cell survival and nutrient absorption

…, RP Sebra, LE Dow, LC Cantley, KY Rhee… - Nature, 2021 - nature.com
Fructose consumption is linked to the rising incidence of obesity and cancer, which are two
of the leading causes of morbidity and mortality globally 1 , 2 . Dietary fructose metabolism …

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

J Marrero, KY Rhee, D Schnappinger, K Pethe… - Proceedings of the …, 2010 - pnas.org
Metabolic adaptation to the host niche is a defining feature of the pathogenicity of
Mycobacterium tuberculosis (Mtb). In vitro, Mtb is able to grow on a variety of carbon sources, but …

High-fructose corn syrup enhances intestinal tumor growth in mice

…, J Roper, Y Kim, Q Chen, SS Gross, KY Rhee… - Science, 2019 - science.org
Excessive consumption of beverages sweetened with high-fructose corn syrup (HFCS) is
associated with obesity and with an increased risk of colorectal cancer. Whether HFCS …

[HTML][HTML] Watson for Oncology and breast cancer treatment recommendations: agreement with an expert multidisciplinary tumor board

…, CR Kumar, A Rauthan, NA Kumar, P Patil, K Rhee… - Annals of …, 2018 - Elsevier
Background Breast cancer oncologists are challenged to personalize care with rapidly changing
scientific evidence, drug approvals, and treatment guidelines. Artificial intelligence (AI) …