User profiles for Kevin C. Chan

Kevin C. Chan

NeuroImaging and Visual Science Laboratory, New York University Grossman School of …
Verified email at nyumc.org
Cited by 3412

An exploratory investigation of the firm size effect

KC Chan, N Chen, DA Hsieh - Journal of Financial Economics, 1985 - Elsevier
We investigate the firm size effect for the period 1958 to 1977 in the framework of a multi-factor
pricing model. The risk-adjusted difference in returns between the top five percent and the …

Does diffusion kurtosis imaging lead to better neural tissue characterization? A rodent brain maturation study

MM Cheung, ES Hui, KC Chan, JA Helpern, L Qi… - Neuroimage, 2009 - Elsevier
Diffusion kurtosis imaging (DKI) can be used to estimate excess kurtosis, which is a dimensionless
measure for the deviation of water diffusion profile from Gaussian distribution. Several …

B-value dependence of DTI quantitation and sensitivity in detecting neural tissue changes

ES Hui, MM Cheung, KC Chan, EX Wu - Neuroimage, 2010 - Elsevier
Recently, remarkable success has been demonstrated in using MR diffusion tensor imaging
(DTI) to characterize white matter. Water diffusion in complex biological tissue …

Cholinergic nervous system and glaucoma: From basic science to clinical applications

MA Faiq, G Wollstein, JS Schuman, KC Chan - Progress in retinal and eye …, 2019 - Elsevier
The cholinergic system has a crucial role to play in visual function. Although cholinergic drugs
have been a focus of attention as glaucoma medications for reducing eye pressure, little is …

Retinal structures and visual cortex activity are impaired prior to clinical vision loss in glaucoma

…, SG Kim, G Wollstein, JS Schuman, KC Chan - Scientific reports, 2016 - nature.com
Glaucoma is the second leading cause of blindness worldwide and its pathogenesis remains
unclear. In this study, we measured the structure, metabolism and function of the visual …

Hippocampal neurochemistry is involved in the behavioural effects of neonatal maternal separation and their reversal by post-weaning environmental enrichment: a …

…, S Liu, G Xi, X Zhang, GJ Teng, KC Chan… - Behavioural brain …, 2011 - Elsevier
Exposure to early life stress results in behavioural changes, and these dysfunctions may
persist throughout adulthood. In this study, we investigated whether hippocampus volume and …

Proton magnetic resonance spectroscopy revealed choline reduction in the visual cortex in an experimental model of chronic glaucoma

KC Chan, K So, EX Wu - Experimental eye research, 2009 - Elsevier
Glaucoma is a neurodegenerative disease of the visual system. While elevated intraocular
pressure is considered to be a major risk factor, the primary cause and pathogenesis of this …

Learning and Memory Alterations Are Associated with Hippocampal N-acetylaspartate in a Rat Model of Depression as Measured by 1H-MRS

G Xi, J Hui, Z Zhang, S Liu, X Zhang, G Teng, KC Chan… - PloS one, 2011 - journals.plos.org
It is generally accepted that cognitive processes, such as learning and memory, are affected
in depression. The present study used a rat model of depression, chronic unpredictable mild …

MRI of late microstructural and metabolic alterations in radiation‐induced brain injuries

KC Chan, P Khong, MM Cheung… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To evaluate the late effects of radiation‐induced damages in the rat brain by
means of in vivo multiparametric MRI. Materials and Methods The right hemibrains of seven …

Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function

…, ET Sakalli, CC Westrick, G Hussey, KC Chan… - Scientific reports, 2019 - nature.com
Injury to retinal ganglion cells (RGC), central nervous system neurons that relay visual
information to the brain, often leads to RGC axon degeneration and permanently lost visual …