1,25‐Dihydroxyvitamin D3 as Well as Its Analogue OCT Lower Blood Calcium Through Inhibition of Bone Resorption in Hypercalcemic Rats with Continuous …

KI Endo, K Katsumata, M Hirata… - Journal of Bone and …, 2000 - academic.oup.com
The effects of 1,25‐dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] and its analogue 22‐oxa‐1,25(OH)
2 D 3 (22‐oxacalcitriol) (OCT) on calcium and bone metabolism were examined in an …

Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity

M Endoh, TA Endo, T Endoh, K Isono, J Sharif… - PLoS …, 2012 - journals.plos.org
… This hypothesis, however, needs rigorous validation because this study was performed
by using Ring1B single knockout (KO) cells, in which Ring1A-catalyzed H2AK119u1 still …

Genetic diversity and genetic structure of Northern Goshawk (Accipiter gentilis) populations in eastern Japan and Central Asia

Y Takaki, T Kawahara, H Kitamura, K Endo… - Conservation Genetics, 2009 - Springer
Japanese goshawk was classified as a vulnerable species in the Red Data Book. There
have been possibilities of a decrease of genetic diversity accompanied by habitat loss and …

[PDF][PDF] An Attention-based Regression Model for Grounding Textual Phrases in Images.

K Endo, M Aono, E Nichols, K Funakoshi - IJCAI, 2017 - ijcai.org
Grounding, or localizing, a textual phrase in an image is a challenging problem that is integral
to visual language understanding. Previous approaches to this task typically make use of …

USP8 prevents aberrant NF-κB and Nrf2 activation by counteracting ubiquitin signals from endosomes

A Endo, T Fukushima, C Takahashi, H Tsuchiya… - Journal of Cell …, 2024 - rupress.org
… In mice, conventional knockout of USP8 causes embryonic lethality early in development
and conditional knockout leads to rapid death in adult mice (Niendorf et al., 2007). In addition, …

Multigene knockout utilizing off-target mutations of the CRISPR/Cas9 system in rice

M Endo, M Mikami, S Toki - Plant and Cell Physiology, 2015 - academic.oup.com
… effective tool for multigene knockout of homeologous and … of achieving multiparalogous
gene knockout by utilizing off-… -CDKA and CDKB gene knockout by taking advantage of off-…

PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes

M Endoh, TA Endo, J Shinga, K Hayashi, A Farcas… - Elife, 2017 - elifesciences.org
… in KO) or blue (down-regulated in KO) lines. Genes silenced in Ctrl but active in KO are …
p-values for the difference of expression changes between Ctrl and KO were calculated by …

C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammatio

M Endo, M Mori, S Akira, T Gotoh - The Journal of Immunology, 2006 - journals.aai.org
… lavage fluid, was attenuated in the Chop knockout mice. Caspase-11, which is needed for the
… The induction of caspase-11 by LPS was suppressed in Chop knockout mice. Caspase-11 …

Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart

J Endo, M Sano, T Katayama, T Hishiki… - Circulation …, 2009 - ahajournals.org
… Heterozygous knockout of Atf4 blunted the increase in intracellular glutathione levels in
Aldh2*2 Tg hearts, thereby attenuating the oxidative stress–resistant phenotype. Furthermore, …

Arabidopsis MEB3 functions as a vacuolar metal transporter to regulate iron accumulation in roots

K Endo, AK Basak, A Wilkens, M Mirzaei… - Frontiers in Plant …, 2025 - frontiersin.org
… Iron but not zinc levels were reduced in meb3 knockout mutant roots, suggesting that the
knockout reduced iron storage capacity in roots. At high iron concentration, meb3 mutants …