Mesenchymal stem cells (MSCs) represent a promising biological therapeutic option as an
osteoarthritis (OA)-modifying treatment. MSCs secrete factors that can counteract …

Surgery of long bone metastases is associated with a significant risk of perioperative blood
loss, which may necessitate blood transfusion. Successful embolization (> 70% obliteration …

Background: Platelet-rich plasma (PRP) has recently been postulated as a treatment for
osteoarthritis (OA). Although anabolic effects of PRP on chondrocytes are well documented, no …

Introduction Currently, antibiotic treatment is often a standard dosing regimen in bone and
joint infections (BJI). However, it remains unknown if exposure at the target-site is adequate. …

Progression and persistence of malignancies are influenced by the local tumor
microenvironment, and future eradication of currently incurable tumors will, in part, hinge on our …

The objective of the present study was to investigate whether treatment of articular cartilage
with hyaluronidase and collagenase enhances histological and mechanical integration of a …

Background: Osteoarthritis (OA) is a degenerative joint disease leading to pain and disability
for which no curative treatment exists. A promising biological treatment for OA is intra-…

We studied the effects of intra‐articularly injected bone marrow derived mesenchymal stem
cells (MSCs), as well as freshly isolated bone marrow mononuclear cells (BMMNCs), on pain…

BACKGROUND Acetabular component positioning in total hip arthroplasty (THA) is of key
importance to ensure satisfactory post-operative outcomes and to minimize the risk of …

In articular cartilage repair, cells that will be responsible for the formation of repair tissue are
often exposed to an osteochondral environment. To study cartilage repair mechanisms in …