Which three-dimensional characteristics make efficient inhibitors of protein–protein interactions?

MA Kuenemann, LML Bourbon, CM Labbé… - Journal of chemical …, 2014 - ACS Publications
The specific properties of protein–protein interactions (PPI) (flat, large and hydrophobic) make
them harder to tackle with low-molecular-weight compounds. Learning from the properties …

[BOOK][B] Bourbon 101

AWA Schmid - 2023 - books.google.com
… In fact, statistics tell us there are nearly two barrels of aging bourbon for every Bluegrass …
known as bourbon's home base, for bourbon lovers everywhere, the act of drinking bourbon is …

[BOOK][B] Kentucky Bourbon Country: The Essential Travel Guide

S Reigler - 2020 - books.google.com
… Developed by local art collectors Laura Lee Brown (yes, another bourbon Brown) and her
husband, Steve Wilson, it is the flagship for a series of museum/hotels they are opening in …

[BOOK][B] Kentucky bourbon whiskey: an American heritage

MR Veach - 2013 - books.google.com
… of the history of bourbon. I also had excel… bourbon was fermented, distilled, and aged; Mike
what makes a good bourbon good and a bad bourbon bad; and Chris how to market bourbon

An exploration of the 3D chemical space has highlighted a specific shape profile for the compounds intended to inhibit protein-protein interactions

MA Kuenemann, LML Bourbon, CM Labbé… - BMC …, 2015 - Springer
Background The vital role of Protein-Protein Interactions (PPI) for Life makes them the
subject of a growing number of drug discovery projects. Yet, the specific properties of PPI (often …

[BOOK][B] More Kentucky Bourbon Cocktails

J Perrine, S Reigler - 2016 - books.google.com
… Kentucky Bourbon Festival in Bardstown, Kentucky, where we present a program called
Bourbon … contemporary art owned by Brown-Forman bourbon heiress Laura Lee Brown and her …

[PDF][PDF] Facts related to the collection of biological samples in the National Health Examination Survey-Portuguese Component of the European Health Examination …

…, E Sousa, AM Vicente, M Bourbon… - ICHG 2011 Scientific …, 2011 - academia.edu
… The serum (8.5 ml), fluoride (2 ml) and EDTA tubes for the separation of plasma (4 ml) were
Laura Ayres (Faro) where they were collected by a carrier, arriving at INSA at 10:00 the next …

Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study

…, L Zuurbier, K Al-Waili, F Sadiq, K Chlebus, M Bourbon… - The Lancet, 2022 - thelancet.com
Background Homozygous familial hypercholesterolaemia (HoFH) is a rare inherited disorder
resulting in extremely elevated low-density lipoprotein cholesterol levels and premature …

Sex differences in diagnosis, treatment, and cardiovascular outcomes in homozygous familial hypercholesterolemia

…, FF Bitar, V Blaha, K Bonomo, M Bourbon… - JAMA …, 2024 - jamanetwork.com
Importance Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition
characterized by extremely increased low-density lipoprotein (LDL) cholesterol levels and …

Phenotypical, clinical, and molecular aspects of adults and children with homozygous familial hypercholesterolemia in iberoamerica

…, ÁJR Morales, P Mata, M Bourbon… - … , and vascular biology, 2020 - ahajournals.org
Bourbon has received project grants from Alexion, Regeneron, Praxis, and Akcea. RD Santos
has received honoraria related to consulting, research, or speaker activities from Amgen, …