User profiles for Laura M. Parkes

Laura M Parkes

University of Manchester
Verified email at manchester.ac.uk
Cited by 10200

Recommended implementation of arterial spin‐labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European …

…, BJ MacIntosh, LM Parkes, M Smits… - Magnetic resonance …, 2015 - Wiley Online Library
This review provides a summary statement of recommended implementations of arterial
spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study …

Normal cerebral perfusion measurements using arterial spin labeling: reproducibility, stability, and age and gender effects

LM Parkes, W Rashid, DT Chard… - Magnetic Resonance in …, 2004 - Wiley Online Library
Before meaningful conclusions can be drawn from clinical measures of cerebral blood
perfusion, the precision of the measurement must be determined and set in the context of inter‐ …

Localizing human visual gamma-band activity in frequency, time and space

…, JM Schoffelen, R Oostenveld, LM Parkes… - Neuroimage, 2006 - Elsevier
Neuronal gamma-band (30–100 Hz) synchronization subserves fundamental functions in
neuronal processing. However, different experimental approaches differ widely in their …

Blood–brain barrier leakage is increased in Parkinson's disease

…, GJM Parker, HCA Emsley, LM Parkes - Frontiers in …, 2020 - frontiersin.org
Background Blood–brain barrier (BBB) disruption has been noted in animal models of
Parkinson’s disease (PD) and forms the basis of the vascular hypothesis of neurodegeneration, …

Improved accuracy of human cerebral blood perfusion measurements using arterial spin labeling: accounting for capillary water permeability

LM Parkes, PS Tofts - … in Medicine: An Official Journal of the …, 2002 - Wiley Online Library
A two‐compartment exchange model for perfusion quantification using arterial spin labeling
(ASL) is presented, which corrects for the assumption that the capillary wall has infinite …

[HTML][HTML] Multivoxel fMRI analysis of color tuning in human primary visual cortex

LM Parkes, JBC Marsman, DC Oxley… - Journal of …, 2009 - iovs.arvojournals.org
We use multivoxel pattern analysis (MVPA) to study the spatial clustering of color-selective
neurons in the human brain. Our main objective was to investigate whether MVPA reveals the …

International multicenter analysis of brain structure across clinical stages of Parkinson's disease

…, CT McMillan, TR Melzer, LM Parkes… - Movement …, 2021 - Wiley Online Library
Background Brain structure abnormalities throughout the course of Parkinson's disease have
yet to be fully elucidated. Objective Using a multicenter approach and harmonized analysis …

Quantifying the spatial resolution of the gradient echo and spin echo BOLD response at 3 Tesla

LM Parkes, JV Schwarzbach, AA Bouts… - Magnetic resonance …, 2005 - Wiley Online Library
The blood oxygen level dependent (BOLD) response, as measured with fMRI, offers good
spatial resolution compared to other non‐invasive neuroimaging methods. The use of a spin …

A systematic review of glucose transport alterations in Alzheimer's disease

…, HCA Emsley, O Sparasci, LM Parkes… - Frontiers in …, 2021 - frontiersin.org
Introduction: Alzheimer's disease (AD) is characterized by cerebral glucose hypometabolism.
Hypometabolism may be partly due to reduced glucose transport at the blood-brain barrier (…

A comparison of dual gradient‐echo and spin‐echo fMRI of the inferior temporal lobe

…, SR Welbourne, K Embleton, LM Parkes - Human brain …, 2014 - Wiley Online Library
Magnetic susceptibility differences at tissue interfaces lead to signal loss in conventional
gradient‐echo (GE) EPI. This poses a problem for fMRI in language and memory paradigms, …