User profiles for Leu-Wei Lo

Leu-Wei Lo

Verified email at nhri.org.tw
Cited by 6181

Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles

…, CT Chen, CS Yang, JA Ho, CY Mou, LW Lo - Biomaterials, 2010 - Elsevier
Nanoparticle-assisted drug delivery has been emerging as an active research area in
recent years. The in vivo biodistribution of nanoparticle and its following mechanisms of …

Intracellular pH-responsive mesoporous silica nanoparticles for the controlled release of anticancer chemotherapeutics

…, JS Souris, CS Yang, CY Mou, LW Lo - Angewandte Chemie …, 2010 - hub.tmu.edu.tw
Cut here to cure: Doxorubicin attached to pH-sensitive mesoporous silica nanoparticles (MSN-hydrazone-Dox)
shows potential in the chemotherapeutic treatment of liver cancer. …

Near‐infrared mesoporous silica nanoparticles for optical imaging: Characterization and in vivo biodistribution

…, CT Chen, CY Mou, CS Yang, LW Lo - Advanced Functional …, 2009 - Wiley Online Library
The characterization of near‐infrared (NIR) mesoporous silica nanoparticles (MSN) suitable
for in vivo optical imaging with high efficiency is presented. Trimethylammonium groups …

Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring …

LW Lo, CJ Koch, DF Wilson - Analytical biochemistry, 1996 - Elsevier
Oxygen-dependent quenching of phosphorescence is a function of the frequency of collision
between the phosphor and molecular oxygen and of the efficiency of energy transfer during …

Mesoporous silica nanoparticles functionalized with an oxygen-sensing probe for cell photodynamic therapy: potential cancer theranostics

…, CS Yang, FG Tseng, CY Mou, LW Lo - Journal of Materials …, 2009 - pubs.rsc.org
Functionalization of mesoporous silica nanoparticles (MSNs) with Pd-porphyrins for cancer
cell photodynamic therapy is reported. The composite platform, MSN–PdTPP, expands the …

Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics—the trio of imaging, targeting and therapy

…, CS Yang, CY Mou, CT Chen, LW Lo - Journal of Materials …, 2010 - pubs.rsc.org
In this work we report the development of the tri-functionalized mesoporous silica nanoparticles
(MSNs) for use as theranostic compounds that orchestrate the trio of imaging, target and …

Synthesis and characterization of positive‐charge functionalized mesoporous silica nanoparticles for oral drug delivery of an anti‐inflammatory drug

CH Lee, LW Lo, CY Mou… - Advanced Functional …, 2008 - Wiley Online Library
We synthesized mesoporous silica nanoparticles (MSN) with different densities of surface
positive charges. The positive surface charge was generated by incorporating …

Recent advances in nanoparticle-based Förster resonance energy transfer for biosensing, molecular imaging and drug release profiling

…, CP Liu, JS Souris, CT Chen, CY Mou, LW Lo - International journal of …, 2012 - mdpi.com
Förster resonance energy transfer (FRET) may be regarded as a “smart” technology in the
design of fluorescence probes for biological sensing and imaging. Recently, a variety of …

In vitro studies of functionalized mesoporous silica nanoparticles for photodynamic therapy

HL Tu, YS Lin, HY Lin, Y Hung, LW Lo, YF Chen… - Advanced …, 2009 - hub.tmu.edu.tw
A simple surface modification process that conjugates a photosensitizer, photoporphyrin IX (PpIX),
with mesoporous silica nanoparticles (MSNs) through covalent bonding to yield PpIX-…

Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells

JJ Chiu, LJ Chen, PL Lee, CI Lee, LW Lo… - Blood, The Journal …, 2003 - ashpublications.org
Vascular endothelial cells (ECs), which exist in close proximity to vascular smooth muscle
cells (SMCs), are constantly subjected to blood flow–induced shear stress. Although the effect …