User profiles for Leu-Wei Lo
Leu-Wei LoVerified email at nhri.org.tw Cited by 6181 |
Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles
…, CT Chen, CS Yang, JA Ho, CY Mou, LW Lo - Biomaterials, 2010 - Elsevier
Nanoparticle-assisted drug delivery has been emerging as an active research area in
recent years. The in vivo biodistribution of nanoparticle and its following mechanisms of …
recent years. The in vivo biodistribution of nanoparticle and its following mechanisms of …
Intracellular pH-responsive mesoporous silica nanoparticles for the controlled release of anticancer chemotherapeutics
…, JS Souris, CS Yang, CY Mou, LW Lo - Angewandte Chemie …, 2010 - hub.tmu.edu.tw
Cut here to cure: Doxorubicin attached to pH-sensitive mesoporous silica nanoparticles (MSN-hydrazone-Dox)
shows potential in the chemotherapeutic treatment of liver cancer. …
shows potential in the chemotherapeutic treatment of liver cancer. …
Near‐infrared mesoporous silica nanoparticles for optical imaging: Characterization and in vivo biodistribution
…, CT Chen, CY Mou, CS Yang, LW Lo - Advanced Functional …, 2009 - Wiley Online Library
The characterization of near‐infrared (NIR) mesoporous silica nanoparticles (MSN) suitable
for in vivo optical imaging with high efficiency is presented. Trimethylammonium groups …
for in vivo optical imaging with high efficiency is presented. Trimethylammonium groups …
Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring …
LW Lo, CJ Koch, DF Wilson - Analytical biochemistry, 1996 - Elsevier
Oxygen-dependent quenching of phosphorescence is a function of the frequency of collision
between the phosphor and molecular oxygen and of the efficiency of energy transfer during …
between the phosphor and molecular oxygen and of the efficiency of energy transfer during …
Mesoporous silica nanoparticles functionalized with an oxygen-sensing probe for cell photodynamic therapy: potential cancer theranostics
Functionalization of mesoporous silica nanoparticles (MSNs) with Pd-porphyrins for cancer
cell photodynamic therapy is reported. The composite platform, MSN–PdTPP, expands the …
cell photodynamic therapy is reported. The composite platform, MSN–PdTPP, expands the …
Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics—the trio of imaging, targeting and therapy
…, CS Yang, CY Mou, CT Chen, LW Lo - Journal of Materials …, 2010 - pubs.rsc.org
In this work we report the development of the tri-functionalized mesoporous silica nanoparticles
(MSNs) for use as theranostic compounds that orchestrate the trio of imaging, target and …
(MSNs) for use as theranostic compounds that orchestrate the trio of imaging, target and …
Synthesis and characterization of positive‐charge functionalized mesoporous silica nanoparticles for oral drug delivery of an anti‐inflammatory drug
CH Lee, LW Lo, CY Mou… - Advanced Functional …, 2008 - Wiley Online Library
We synthesized mesoporous silica nanoparticles (MSN) with different densities of surface
positive charges. The positive surface charge was generated by incorporating …
positive charges. The positive surface charge was generated by incorporating …
Recent advances in nanoparticle-based Förster resonance energy transfer for biosensing, molecular imaging and drug release profiling
…, CP Liu, JS Souris, CT Chen, CY Mou, LW Lo - International journal of …, 2012 - mdpi.com
Förster resonance energy transfer (FRET) may be regarded as a “smart” technology in the
design of fluorescence probes for biological sensing and imaging. Recently, a variety of …
design of fluorescence probes for biological sensing and imaging. Recently, a variety of …
In vitro studies of functionalized mesoporous silica nanoparticles for photodynamic therapy
A simple surface modification process that conjugates a photosensitizer, photoporphyrin IX (PpIX),
with mesoporous silica nanoparticles (MSNs) through covalent bonding to yield PpIX-…
with mesoporous silica nanoparticles (MSNs) through covalent bonding to yield PpIX-…
Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells
Vascular endothelial cells (ECs), which exist in close proximity to vascular smooth muscle
cells (SMCs), are constantly subjected to blood flow–induced shear stress. Although the effect …
cells (SMCs), are constantly subjected to blood flow–induced shear stress. Although the effect …