Lycium barbarum berries, also named wolfberry, Fructus lycii, and Goji berries, have been
used in the People’s Republic of China and other Asian countries for more than 2,000 years …

Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities, …

Histone modifications are associated with many fundamental biological processes in cells.
An emerging notion from recent studies is that meiosis stage-dependent histone …

G-protein-coupled receptors (GPCRs) are critically regulated by β-arrestins, which not only
desensitize G-protein signalling but also initiate a G-protein-independent wave of signalling 1 …

p53 is activated in response to various genotoxic stresses resulting in cell cycle arrest or
apoptosis 1 , 2 . It is well documented that DNA damage leads to phosphorylation and activation …

Background In December, 2007, a family cluster of two individuals infected with highly
pathogenic avian influenza A (H5N1) virus was identified in Jiangsu Province, China. Field and …

Circular RNAs (circRNAs), highly expressed in the central nervous system, are involved in
various regulatory processes and implicated in some pathophysiology. However, the potential …

Mitogen-activated protein kinase (MAPK) cascades are involved in biotic and abiotic stress
responses. In plants, MAPKs are classified into four groups, designated A–D. Information …

Objective To explore the effects of resveratrol-induced apoptosis and autophagy in T-cell acute
lymphoblastic leukemia (T-ALL) cells and potential molecular mechanisms. Methods The …

Chimeric antigen receptor T (CAR-T) cells have been proposed for HIV-1 treatment but have
not yet demonstrated desirable therapeutic efficacy. Here, we report newly developed anti-…