BACKGROUND: Although rural residents are more likely to be diagnosed with more
advanced cancers and to die of cancer, little is known about rural‐urban disparities in self‐reported …

Prostate cancer has a strong familial component but uncovering the molecular basis for
inherited susceptibility for this disease has been challenging. Recently, a rare, recurrent …

African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies
have examined T2DM using genome-wide association approaches in this ethnicity. The aim …

A genome-wide association study was performed using the Affymetrix 6.0 chip to identify
genes associated with diabetic nephropathy in African Americans. Association analysis was …

Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical
atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, …

Variation in body fat distribution contributes to the metabolic sequelae of obesity. The genetic
determinants of body fat distribution are poorly understood. The goal of this study was to …

Purpose Rural US adults have increased risk of poor outcomes after cancer, including
increased cancer mortality. Rural–urban differences in health behaviors have been identified in …

Aortic calcification is an important independent predictor of future cardiovascular events. We
performed a genome-wide association meta-analysis to determine SNPs associated with …

PPP2R2A, mapped to 8p21.2, codes for the α isoform of the regulatory B55 subfamily of
protein phosphatase 2 (PP2A). PP2A is one of the four major serine/threonine phosphatases …

Single nucleotide polymorphisms (SNPs) in MYH9 and APOL1 on chromosome 22 (c22)
are powerfully associated with non-diabetic end-stage renal disease (ESRD) in African …