An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study

L Cai, DMJ Lambregts, GL Beets, M Maas… - NPJ Precision …, 2024 - nature.com
The classification of extramural vascular invasion status using baseline magnetic resonance
imaging in rectal cancer has gained significant attention as it is an important prognostic …

Association of white matter hyperintensities with BMD, incident fractures, and falls in the UK Biobank cohort

L Cai, X Lv, X Li, X Wang, H Ma… - Journal of bone and …, 2024 - academic.oup.com
Osteoporosis is the most common metabolic bone disease globally, which increases the
healthcare service burden. Recent studies have linked higher white matter hyperintensities (…

Comparison and risk factors analysis of multiple breast cancer screening methods in the evaluation of breast non-mass-like lesions

J Zhang, L Cai, X Pan, L Chen, M Chen, D Yan… - BMC Medical …, 2022 - Springer
Objective To compare multiple breast cancer screening methods for evaluating breast non-mass-like
lesions (NMLs), and investigate new best screening method for breast non-mass-…

Isotemporal substitution modeling on sedentary behaviors and physical activity with mortality among people with different diabetes statuses: a prospective cohort study …

Z Chen, L Cai, Q Qin, X Li, S Lu… - … of Physical Activity …, 2024 - journals.humankinetics.com
Background : To assess the associations of replacing sedentary behavior with different
types of physical activity with mortality among the US adults of varying diabetes statuses. …

Improving Rectal Tumor Segmentation with Anomaly Fusion Derived from Anatomical Inpainting: A Multicenter Study

L Cai, MA Abdelatty, L Han, DMJ Lambregts… - medRxiv, 2024 - medrxiv.org
Accurate rectal tumor segmentation using magnetic resonance imaging (MRI) is paramount
for effective treatment planning. It allows for volumetric and other quantitative tumor …

An improved automatic system for aiding the detection of colon polyps using deep learning

L Cai, R Beets-Tan, S Benson - 2021 IEEE EMBS International …, 2021 - ieeexplore.ieee.org
Colorectal cancer is responsible for the most cancer deaths after lung cancer. It has been
well-established that early detection and removal of polyps can prevent colorectal cancer. It is …

Degree of Joint Risk Factor Control and Incident Fracture Outcomes in Individuals With Type 2 Diabetes

H Huang, J Cai, H Hu, L Cai, L Qi… - The Journal of Clinical …, 2025 - academic.oup.com
Context Individuals with type 2 diabetes have a higher fracture risk than the general
population. However, the association between joint risk factor control and fracture risk in this …

Study on the levels of N-nitrosamine compounds and untargeted metabolomics in patients with colorectal cancer

Z Luo, H Wang, S Lin, L Liao, L Cai, X Zhang… - Analytical and …, 2022 - Springer
Plasma samples were collected from 34 patients with advanced CRC and 92 healthy
persons (control group), and the levels of 9 VNAs were measured using GC–MS. Untargeted …

CEUS Helps to Rerate Small Breast Tumors of BI‐RADS Category 3 and Category 4

J Zhang, L Cai, L Chen, J Dai… - BioMed Research …, 2014 - Wiley Online Library
Purpose. The primary aim of this study was to explore if classification, whether using the BI‐RADS
categories based on CEUS or conventional ultrasound, was conducive to the …

Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC

J Cai, L Fang, Y Huang, R Li, X Xu, Z Hu… - Nature …, 2017 - nature.com
Cancer chemoresistance and metastasis are tightly associated features. However, whether
they share common molecular mechanisms and thus can be targeted with one common …