Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy

HT Li, L Xu, DJ Weisenberger, M Li, W Zhou… - Nature …, 2022 - nature.com
Retinoblastoma (RB) is a cancer that forms in the developing retina of babies and toddlers.
The goal of therapy is to cure the tumor, save the eye and maximize vision. However, it is …

Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients

…, C Zong, H Bai, AR Chapman, J Zhao, L Xu… - Proceedings of the …, 2013 - pnas.org
Circulating tumor cells (CTCs) enter peripheral blood from primary tumors and seed metastases.
The genome sequencing of CTCs could offer noninvasive prognosis or even diagnosis, …

Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing

…, W Fan, M Yang, J Li, AR Chapman, P Zhu, X Hu, L Xu… - science, 2012 - science.org
Meiotic recombination creates genetic diversity and ensures segregation of homologous
chromosomes. Previous population analyses yielded results averaged among individuals and …

[HTML][HTML] Genome analyses of single human oocytes

Y Hou, W Fan, L Yan, R Li, Y Lian, J Huang, J Li, L Xu… - Cell, 2013 - cell.com
Single-cell genome analyses of human oocytes are important for meiosis research and
preimplantation genomic screening. However, the nonuniformity of single-cell whole-genome …

The effects of exercise for cognitive function in older adults: a systematic review and meta-analysis of randomized controlled trials

L Xu, H Gu, X Cai, Y Zhang, X Hou, J Yu… - International journal of …, 2023 - mdpi.com
Background: Physical exercise can slow down the decline of the cognitive function of the
older adults, yet the review evidence is not conclusive. The purpose of this study was to …

[HTML][HTML] Risk factors of flatfoot in children: a systematic review and meta-analysis

L Xu, H Gu, Y Zhang, T Sun, J Yu - International journal of environmental …, 2022 - mdpi.com
Background: This study aimed to explore the risk factors for flatfoot in children and adolescents
to provide a reference basis for studying foot growth and development in children and …

[HTML][HTML] Aqueous humor markers in retinoblastoma, a review

BK Ghiam, L Xu, JL Berry - Translational Vision Science & …, 2019 - jov.arvojournals.org
Purpose: Retinoblastoma (Rb) is the most common primary intraocular cancer in children.
Unlike with most solid tumors, direct biopsy is contraindicated due to risk of tumor …

Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by next-generation sequencing with linkage analyses

L Yan, L Huang, L Xu, J Huang, F Ma, X Zhu… - Proceedings of the …, 2015 - pnas.org
In vitro fertilization (IVF), preimplantation genetic diagnosis (PGD), and preimplantation
genetic screening (PGS) help patients to select embryos free of monogenic diseases and …

Facile and scalable synthesis of mesoporous composite materials from coal gasification fine slag for enhanced adsorption of malachite green

Q Qiao, H Zhou, F Guo, R Shu, S Liu, L Xu… - Journal of Cleaner …, 2022 - Elsevier
The recycling of the solid wastes produced in the industrial process and converting them
into functional materials with unique structures are of great significance for the sustainable …

Potential of aqueous humor as a surrogate tumor biopsy for retinoblastoma

JL Berry, L Xu, AL Murphree, S Krishnan… - JAMA …, 2017 - jamanetwork.com
Importance Retinoblastoma (Rb) is one of the first tumors to have a known genetic etiology.
However, because biopsy of this tumor is contraindicated, it has not been possible to define …