User profiles for Lizhen Zheng
Li-Zhen ZhengThe Chinese University of Hong Kong Verified email at ort.cuhk.edu.hk Cited by 3741 |
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
Orthopedic implants containing biodegradable magnesium have been used for fracture repair
with considerable efficacy; however, the underlying mechanisms by which these implants …
with considerable efficacy; however, the underlying mechanisms by which these implants …
A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy
Metabolic skeletal disorders associated with impaired bone formation are a major clinical
challenge. One approach to treat these defects is to silence bone-formation–inhibitory genes …
challenge. One approach to treat these defects is to silence bone-formation–inhibitory genes …
Dynamic and cell-infiltratable hydrogels as injectable carrier of therapeutic cells and drugs for treating challenging bone defects
Biopolymeric hydrogels have been widely used as carriers of therapeutic cells and drugs for
biomedical applications. However, most conventional hydrogels cannot be injected after …
biomedical applications. However, most conventional hydrogels cannot be injected after …
Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis
Y Li, J Xu, J Mi, X He, Q Pan, L Zheng, H Zu, Z Chen… - Biomaterials, 2021 - Elsevier
Critical size bone defects are frequently caused by accidental trauma, oncologic surgery,
and infection. Distraction osteogenesis (DO) is a useful technique to promote the repair of …
and infection. Distraction osteogenesis (DO) is a useful technique to promote the repair of …
Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically used …
medical and socioeconomic burdens. Intra-articular administration of agents is clinically used …
Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis
…, C Hopkins, H Wang, H Yao, J Mi, L Zheng… - Nature …, 2022 - nature.com
Epididymal white adipose tissue (eWAT) secretes an array of cytokines to regulate the
metabolism of organs and tissues in high-fat diet (HFD)-induced obesity, but its effects on bone …
metabolism of organs and tissues in high-fat diet (HFD)-induced obesity, but its effects on bone …
Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: proof-of-concept for prevention of hip joint collapse in bipedal emus and …
Steroid-associated osteonecrosis (SAON) may lead to joint collapse and subsequent joint
replacement. Poly lactic-co-glycolic acid/tricalcium phosphate (P/T) scaffold providing …
replacement. Poly lactic-co-glycolic acid/tricalcium phosphate (P/T) scaffold providing …
[HTML][HTML] Combination of magnesium ions and vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice
Introduction We previously demonstrated that magnesium ions (Mg 2+ ) was a novel therapeutic
alternative for osteoarthritis (OA) through promoting the hypoxia inducible factor-1α (HIF-…
alternative for osteoarthritis (OA) through promoting the hypoxia inducible factor-1α (HIF-…
A bone-targeting delivery system carrying osteogenic phytomolecule icaritin prevents osteoporosis in mice
Targeting delivery system has been widely used in packaging drugs for medical therapies
attributed to its high efficiency and efficacy. A Traditional Chinese Medicine (TCM) formula …
attributed to its high efficiency and efficacy. A Traditional Chinese Medicine (TCM) formula …
64-kb hybrid Josephson-CMOS 4 Kelvin RAM with 400 ps access time and 12 mW read power
T Van Duzer, L Zheng, SR Whiteley… - IEEE Transactions …, 2012 - ieeexplore.ieee.org
We have designed, simulated, fabricated, and tested a 64-kb hybrid Josephson-CMOS
memory using a 5 mm × 5 mm Josephson interface chip and a 2.0 × 1.5 mm CMOS chip. The …
memory using a 5 mm × 5 mm Josephson interface chip and a 2.0 × 1.5 mm CMOS chip. The …