HIV evolution: CTL escape mutation and reversion after transmission
…, M Altfeld, C Brander, C Dixon, D Ramduth, P Jeena… - Nature medicine, 2004 - nature.com
Within-patient HIV evolution reflects the strong selection pressure driving viral escape from
cytotoxic T-lymphocyte (CTL) recognition. Whether this intrapatient accumulation of escape …
cytotoxic T-lymphocyte (CTL) recognition. Whether this intrapatient accumulation of escape …
International perspectives, progress, and future challenges of paediatric HIV infection
…, G Tudor-Williams, P Jeena, S Burchett, P Goulder - The Lancet, 2007 - thelancet.com
Paediatric HIV infection is a growing health challenge worldwide, with an estimated 1500
new infections every day. In developed countries, well established prevention programmes …
new infections every day. In developed countries, well established prevention programmes …
Advances in childhood immunisation in South Africa: where to now? Programme managers' views and evidence from systematic reviews
CS Wiysonge, NJ Ngcobo, PM Jeena, SA Madhi… - BMC Public Health, 2012 - Springer
Background The Expanded Programme on Immunisation (EPI) is one of the most powerful
and cost-effective public health programmes to improve child survival. We assessed …
and cost-effective public health programmes to improve child survival. We assessed …
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection
…, MM Addo, L Ruiz, D Ramduth, P Jeena… - Journal of Experimental …, 2004 - rupress.org
… and 147 was associated with expression of B57 (P 0.0001 and P 0.0001, respectively,
Fisher’s exact test), as well as in clade B–infected subjects (P 0.03 and P 0.0006, respectively). …
Fisher’s exact test), as well as in clade B–infected subjects (P 0.03 and P 0.0006, respectively). …
Effect of age, polymicrobial disease, and maternal HIV status on treatment response and cause of severe pneumonia in South African children: a prospective …
LM McNally, PM Jeena, K Gajee, SA Thula, AW Sturm… - The Lancet, 2007 - thelancet.com
Background HIV-related pneumonia is the main cause of paediatric hospital admissions in
southern Africa. We aimed to measure predictors of treatment failure and the cause of non-…
southern Africa. We aimed to measure predictors of treatment failure and the cause of non-…
[HTML][HTML] Management of acute fever in children: Consensus recommendations for community and primary healthcare providers in sub-Saharan Africa
Fever is one of the most common reasons for unwell children presenting to pharmacists and
primary healthcare practitioners. Currently there are no guidelines for assessment and …
primary healthcare practitioners. Currently there are no guidelines for assessment and …
Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study
…, M Hassan, P Hibberd, JM Lozano, P Jeena… - The Lancet, 2004 - thelancet.com
… Diagnostic capabilities in most developing countries are few for both HIV infection and P
jiroveci pneumonia, and children with respiratory infection are usually managed on the basis of …
jiroveci pneumonia, and children with respiratory infection are usually managed on the basis of …
Assessment of clinical outcomes among children and adolescents hospitalized with COVID-19 in 6 sub-Saharan African countries
…, LN Byamungu, R Masekela, PM Jeena… - JAMA …, 2022 - jamanetwork.com
Importance Little is known about COVID-19 outcomes among children and adolescents in
sub-Saharan Africa, where preexisting comorbidities are prevalent. Objective To assess the …
sub-Saharan Africa, where preexisting comorbidities are prevalent. Objective To assess the …
Etiology of bacteremia in young infants in six countries
Background: Neonatal illness is a leading cause of death worldwide; sepsis is one of the
main contributors. The etiologies of community-acquired neonatal bacteremia in developing …
main contributors. The etiologies of community-acquired neonatal bacteremia in developing …
Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa
…, PM Jeena, S Jepsen, P Abbink… - Journal of clinical …, 2006 - journals.asm.org
We assessed neutralizing antibody titers to adenovirus serotype 5 (Ad5) and six rare
adenovirus serotypes, serotypes 11, 35, 50, 26, 48, and 49, in pediatric populations in sub-Saharan …
adenovirus serotypes, serotypes 11, 35, 50, 26, 48, and 49, in pediatric populations in sub-Saharan …