User profiles for Quynh N. Vo
Quynh N. VoUniversity of California, Irvine Verified email at uci.edu Cited by 272 |
The ATM gene is a target for epigenetic silencing in locally advanced breast cancer
QN Vo, WJ Kim, L Cvitanovic, DA Boudreau… - Oncogene, 2004 - nature.com
Several epidemiological studies on ataxia–telangiectasia families indicate that obligate ATM
heterozygotes display an elevated risk for developing breast cancer. However, a molecular …
heterozygotes display an elevated risk for developing breast cancer. However, a molecular …
How μ-opioid receptor recognizes fentanyl
Roughly half of the drug overdose-related deaths in the United States are related to synthetic
opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In …
opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In …
Ataxia-Telangiectasia-Mutated (ATM) Gene in Head and Neck Squamous Cell Carcinoma: Promoter Hypermethylation with Clinical Correlation in 100 Cases
L Ai, QN Vo, C Zuo, L Li, W Ling, JY Suen… - Cancer Epidemiology …, 2004 - aacrjournals.org
The Ataxia-telangiectasia-mutated (ATM) gene product is a well-characterized tumor suppressor
that plays a key role in maintenance of genomic stability. We have recently documented …
that plays a key role in maintenance of genomic stability. We have recently documented …
Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line
W Kim, QN Vo, M Shrivastav, TA Lataxes, KD Brown - Oncogene, 2002 - nature.com
Recent findings suggest that DNA alkylating agents trigger cellular responses that overlap
those activated after ionizing radiation. Moreover, activation of these responses is dependent …
those activated after ionizing radiation. Moreover, activation of these responses is dependent …
Kinetics and mechanism of fentanyl dissociation from the μ-opioid receptor
Driven by illicit fentanyl, opioid related deaths have reached the highest level in 2020.
Currently, an opioid overdose is resuscitated by the use of naloxone, which competitively binds …
Currently, an opioid overdose is resuscitated by the use of naloxone, which competitively binds …
The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms
J Bolt, QN Vo, WJ Kim, AJ McWhorter, J Thomson… - Oral oncology, 2005 - Elsevier
The ATM/p53 pathway plays a critical role in maintenance of genome integrity and can be
targeted for inactivation by a number of characterized mechanisms including somatic genetic/…
targeted for inactivation by a number of characterized mechanisms including somatic genetic/…
Computational Study of Molecular Structure and Self-Association of Tri-n-butyl Phosphates in n-Dodecane
Tri-n-butyl phosphate (TBP) is an important extractant used in the solvent extraction process
for recovering uranium and plutonium from used nuclear fuel. An atomistic molecular …
for recovering uranium and plutonium from used nuclear fuel. An atomistic molecular …
Structure–kinetics relationships of opioids from metadynamics and machine learning analysis
The nation’s opioid overdose deaths reached an all-time high in 2021. The majority of
deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is a FDA-approved …
deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is a FDA-approved …
Quantifying Dimer and Trimer Formation by Tri-n-butyl Phosphates in n-Dodecane: Molecular Dynamics Simulations
Tri-n-butyl phosphate (TBP), a representative of neutral organophosphorous ligands, is an
important extractant used in the solvent extraction process for the recovery of uranium and …
important extractant used in the solvent extraction process for the recovery of uranium and …
Quantifying Dimer and Trimer Formation of Tri-n-butyl Phosphates in Different Alkane Diluents: FTIR Study
Tri-n-butyl phosphate (TBP), a representative of neutral organophosphorous metal-ion-extracting
reagents, is an important ligand used in solvent extraction processes for the recovery of …
reagents, is an important ligand used in solvent extraction processes for the recovery of …