Induction of molecular chaperones is the characteristic protective response to environmental
stress, and is regulated by a transcriptional program that depends on heat shock factor 1 (…

Proper folding of proteins (either newly synthesized or damaged in response to a stressful
event) occurs in a highly regulated fashion. Cytosolic chaperones such as Hsc/Hsp70 are …

Electric-vehicle (EV) battery-swap stations (BSSs) have become important infrastructures for
the development of EVs to extend their driving range. Due to the randomness of batteries' …

Study Design. A cadaveric study comparing the biomechanics of unipedicular versus bipedicular
kyphoplasty in the treatment of osteoporotic vertebral compression fractures. Objectives…

Infection with some viruses can alter cellular mRNA processing to favor viral gene
expression. We present evidence that herpes simplex virus 1 (HSV‐1) protein ICP27, which …

Background Separation from migrant parents threatens the mental health of approximately
61 million left-behind children (LBC) in China. This study compared the prevalence of mental …

A variety of triazole-based monophosphines (ClickPhos) have been prepared via efficient 1,3-dipolar
cycloaddition of readily available azides and acetylenes. Their palladium …

Polycomb repressive complex two (PRC2) has been implicated in embryonic stem (ES) cell
pluripotency; however, the mechanistic roles of this complex are unclear. It was assumed …

The cytoplasm is protected against the perils of protein misfolding by two mechanisms:
molecular chaperones (which facilitate proper folding) and the ubiquitin-proteasome system, …

Background Aberrant expression of circular RNAs contributes to the initiation and progression
of cancers, but the underlying mechanism remains elusive. Methods RNA-seq and qRT-…