The landscape of somatic copy-number alteration across human cancers

…, A Loo, C Hoffman, J Prensner, T Liefeld, Q Gao… - Nature, 2010 - nature.com
A powerful way to discover key genes with causal roles in oncogenesis is to identify
genomic regions that undergo frequent alteration in human cancers. Here we present high-…

Evaluation of effective connectivity of motor areas during motor imagery and execution using conditional Granger causality

Q Gao, X Duan, H Chen - Neuroimage, 2011 - Elsevier
The effective connectivity networks among overlapped core regions recruited by motor execution
(ME) and motor imagery (MI) were explored by means of conditional Granger causality …

Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

A Molla, M Korneyeva, Q Gao, S Vasavanonda… - Nature medicine, 1996 - nature.com
Abstract Analysis of the HIV protease gene from the plasma of HIV–infected patients
revealed substitutions at nine different codons selected in response to monotherapy with the …

The jujube (Ziziphus jujuba Mill.) fruit: a review of current knowledge of fruit composition and health benefits

QH Gao, CS Wu, M Wang - Journal of agricultural and food …, 2013 - ACS Publications
The nutritional jujube ( Ziziphus jujube Mill.) fruit belonging to the Rhamnaceous family grows
mostly in Europe, southern and eastern Asia, and Australia, especially the inland region of …

Developments of 3D printing microfluidics and applications in chemistry and biology: a review

Y He, Y Wu, J Fu, Q Gao, J Qiu - Electroanalysis, 2016 - Wiley Online Library
Three‐dimensional (3D) printing, also called additive manufacturing (AM) or rapid prototyping
(RP), is a layer by layer manufacturing method and now has been widely used in many …

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

F Soldner, D Hockemeyer, C Beard, Q Gao, GW Bell… - Cell, 2009 - cell.com
Induced pluripotent stem cells (iPSCs) derived from somatic cells of patients represent a
powerful tool for biomedical research and may provide a source for replacement therapies. …

Genetic engineering of human pluripotent cells using TALE nucleases

D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao… - Nature …, 2011 - nature.com
Targeted genetic engineering of human pluripotent cells is a prerequisite for exploiting their
full potential. Such genetic manipulations can be achieved using site-specific nucleases. …

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

D Hockemeyer, F Soldner, C Beard, Q Gao… - Nature …, 2009 - nature.com
Realizing the full potential of human embryonic stem cells (hESCs) and induced pluripotent
stem cells (hiPSCs) requires efficient methods for genetic modification. However, techniques …

Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

…, Y Stelzer, S Rangarajan, A D'Alessio, J Zhang, Q Gao… - Cell stem cell, 2014 - cell.com
Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological
characteristics, raising the question of whether an earlier, "naive" state of pluripotency may exist …

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

…, J Laganière, AW Cheng, D Hockemeyer, Q Gao… - Cell, 2011 - cell.com
Patient-specific induced pluripotent stem cells (iPSCs) derived from somatic cells provide a
unique tool for the study of human disease, as well as a promising source for cell …