Exosomes are small membrane-bound vesicles secreted by most cell types. Exosomes
contain various functional proteins, mRNAs and microRNAs (miRNAs) that could be used for …

… Zhiyi Han and Qinyu Ge are partners in clinical research. Qinyu Ge is an assistant professor
at SEU, China. The research interests of his group aim at RNA detection, genomics, and …

Although RNA sequencing (RNA‐seq) has become the most advanced technology for
transcriptome analysis, it also confronts various challenges. As we all know, the workflow of RNA‐…

Cell-free DNA molecules are released into the plasma via apoptotic or necrotic events and
active release mechanisms, which carry the genetic and epigenetic information of its origin …

Objective. Preeclampsia (PE) is a pregnancy‐specific syndrome and one of the leading causes
of maternal and fetal morbidity and mortality. The pathophysiological mechanisms of PE …

Objective To profile the differential expression of plasma miRNAs in gestational diabetes
mellitus (GDM). Methods In a pilot study conducted at a tertiary hospital in China between 2010 …

It is reported that different microRNA (miRNA) profiles can be detected in the blood of cancer
patients. We investigated that whether the key serum miRNAs could discriminate patients …

OBJECTIVE: Among methods for profiling levels of miRNAs, next-generation sequencing (NGS)
has an effective one for genome-wide profiles, which not only can accurately quantify …

BACKGROUND: Circulating miRNAs, as a new family of miRNAs existing in plasma and
serum, had shown great potential to serve as a novel biomarker in body fluid for non-invasive …

Emerging evidence indicates that microRNAs (miRNAs), a class of small non-coding RNAs,
are involved in a number of biological processes. The results of SOLiD™ sequencing were …