… During phase 1 remodeling in cone-sparing forms of retinal disease, the earliest forms of
pathology are revealed by an initiation of photoreceptor stress that induces a cascade of events …

… Though the notion of negative retinal remodeling induced by retinal degenerations is not new,
… Retinal remodeling has three implications we wish to emphasize. 1. Remodeling exposes …

… retinal remodeling in humans has not been coherently summarized. Our goal was to assess
human RP retinas in advanced stages of remodeling … (late stage) retinal remodeling on cone …

… retinal disease models now show that all known retinal degenerations trigger remodeling
and that animal models accurately reflect the phenomena underlying human disease. From …

… of the field of retinal remodeling and its implications for … retinal remodeling poses for each
therapeutic strategy under the premise that understanding the features of retinal remodeling in …

… degeneration, and are seen in retinitis pigmentosa, age-related macular degeneration and
other forms of retinal disease. These processes occur regardless of the precipitating event …

… it has been described for other retinal degenerative diseases. However, the most significant
… of negative retinal plasticity, termed retinal remodeling that involves inner retinal neurons …

… retinal degenerative diseases examined to date including natural, crafted and induced models
demonstrate remodeling … in the retina under traumatic and degenerative retinal disease. …

… inner retina is only moderately affected by photoreceptor loss. Conversely, that … remodeling
of retinal layers located beyond photoreceptors accompanies the end stages of the disease is …

… the nature of retinal remodeling, how it affects the ability of remnant retina to respond to novel
… overview of retinal remodeling and some of the emerging therapeutic strategies for retinal …