User profiles for Robert J. Flassig
Robert J FlassigProfessor at University of Applied Sciences Brandenburg Verified email at th-brandenburg.de Cited by 601 |
Dynamic flux balance modeling to increase the production of high-value compounds in green microalgae
Background Photosynthetic organisms can be used for renewable and sustainable
production of fuels and high-value compounds from natural resources. Costs for design and …
production of fuels and high-value compounds from natural resources. Costs for design and …
Reactor-network synthesis via flux profile analysis
NM Kaiser, RJ Flassig, K Sundmacher - Chemical Engineering Journal, 2018 - Elsevier
Within the framework of elementary process functions (Freund and Sundmacher, 2008) an
approach is developed to derive reactor-network candidates from the solution of a dynamic …
approach is developed to derive reactor-network candidates from the solution of a dynamic …
Quantitative single cell analysis uncovers the life/death decision in CD95 network
…, D Pischel, K Sundmacher, RJ Flassig… - PLoS computational …, 2018 - journals.plos.org
CD95/Fas/APO-1 is a member of the death receptor family that triggers apoptotic and anti-apoptotic
responses in particular, NF-κB. These responses are characterized by a strong …
responses in particular, NF-κB. These responses are characterized by a strong …
Probabilistic reactor design in the framework of elementary process functions
NM Kaiser, RJ Flassig, K Sundmacher - Computers & Chemical …, 2016 - Elsevier
Computational process models in combination with innovative design methodologies
provide a powerful reactor design platform. Yet, model-based design is mostly done in a pure …
provide a powerful reactor design platform. Yet, model-based design is mostly done in a pure …
Knowledge based 2D blade design using multi-objective aerodynamic optimization and a neural network
…, PM Flassig, RJ Flassig… - … Expo: Power for …, 2007 - asmedigitalcollection.asme.org
This paper presents a method to obtain optimized 2D blade sections using expert knowledge,
a multi-criteria optimization approach and a neural network in an automated process. A …
a multi-criteria optimization approach and a neural network in an automated process. A …
Reconstruction and analysis of a carbon-core metabolic network for Dunaliella salina
M Fachet, C Witte, RJ Flassig, LK Rihko-Struckmann… - BMC …, 2020 - Springer
Background The green microalga Dunaliella salina accumulates a high proportion of β-carotene
during abiotic stress conditions. To better understand the intracellular flux distribution …
during abiotic stress conditions. To better understand the intracellular flux distribution …
TRANSWESD: inferring cellular networks with transitive reduction
Motivation: Distinguishing direct from indirect influences is a central issue in reverse
engineering of biological networks because it facilitates detection and removal of false positive …
engineering of biological networks because it facilitates detection and removal of false positive …
Optimal design of stimulus experiments for robust discrimination of biochemical reaction networks
RJ Flassig, K Sundmacher - Bioinformatics, 2012 - academic.oup.com
Motivation: Biochemical reaction networks in the form of coupled ordinary differential equations
(ODEs) provide a powerful modeling tool for understanding the dynamics of biochemical …
(ODEs) provide a powerful modeling tool for understanding the dynamics of biochemical …
A guide to automated apoptosis detection: How to make sense of imaging flow cytometry data
…, JH Buchbinder, K Sundmacher, IN Lavrik, RJ Flassig - PLoS …, 2018 - journals.plos.org
Imaging flow cytometry is a powerful experimental technique combining the strength of
microscopy and flow cytometry to enable high-throughput characterization of cell populations on …
microscopy and flow cytometry to enable high-throughput characterization of cell populations on …
Energy and operating cost assessment of competing harvesting methods for D. salina in a β-carotene production process
K Pirwitz, RJ Flassig, LK Rihko-Struckmann… - Algal research, 2015 - Elsevier
A new evaluation concept to assess microalgal harvesting methods was introduced using β-carotene
production with Dunaliella salina as a case study. Detailed experiments were …
production with Dunaliella salina as a case study. Detailed experiments were …