Purpose To study the power of the epidermal growth factor receptor (EGFR) epiregulin (EREG)
and amphiregulin (AREG) ligands' expression in primary tumors to predict the outcome in …

Background: The outcome of primary sclerosing cholangitis (PSC) has improved by liver
transplantation (LT), but patients often develop malignancies. We analysed morbidity and …

Many modern analytical methods are used to analyze samples issued from an experimental
design, for example, in medical, biological, chemical, or agronomic fields. Those methods …

Insurance companies hold reserves to be able to fulfill future liabilities with respect to the
policies they write. Micro-level reserving methods focus on the development of individual …

00 PORTADILLAS Page 1 This study explores the relative contribution of the overall quality
of attachment to the mother, to the father and to peers (Inventory of Parent and Peer …

An adaptation of the Brier score and the concordance probability is proposed for the two-level
and the three-level random intercept binary regression model. This results in 2 different …

Performance measurement is an essential task once a statistical model is created. The area
under the receiving operating characteristics curve (AUC) is the most popular measure for …

This paper proposes a multistate model with a Semi-Markov dependence structure describing
the different stages in the settlement process of individual claims in general insurance. …

The concordance probability, also called the C-index, is a popular measure to capture the
discriminatory ability of a predictive model. In this article, the definition of this measure is …

Insurance pricing is the process of determining the premiums that policyholders pay in
exchange for insurance coverage. In order to estimate premiums, actuaries use statistical based …