Piezo1-regulated mechanotransduction controls flow-activated lymphatic expansion

…, RP Yu, MN Cooper, IT Cho, J Choi, J Yu… - Circulation …, 2022 - ahajournals.org
Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1)
cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI …

Current understanding of pathological mechanisms of lymphedema

C Sung, S Wang, J Hsu, R Yu, AK Wong - Advances in Wound Care, 2022 - liebertpub.com
Significance: Lymphedema is a common disease that affects hundreds of millions of people
worldwide with significant financial and social burdens. Despite increasing prevalence and …

Nanopatterned bulk metallic glass biosensors

ER Kinser, J Padmanabhan, R Yu, SL Corona, J Li… - ACS …, 2017 - ACS Publications
Nanopatterning as a surface area enhancement method has the potential to increase signal
and sensitivity of biosensors. Platinum-based bulk metallic glass (Pt-BMG) is a …

3D stacking of high-performance processors

…, M Healy, K Kailas, V Puente, R Yu… - 2014 IEEE 20th …, 2014 - ieeexplore.ieee.org
In most 3D work to date, people have looked at two situations: 1) a case in which power
density is not a problem, and the parts of a processor and/or entire processors can be stacked …

Surface energy characterization for die-level Cu hybrid bonding

K Sakuma, R Yu, M Belyansky… - 2022 IEEE 72nd …, 2022 - ieeexplore.ieee.org
The characteristics and quality of the bonding interface in hybrid bonding vary greatly
depending on physical and chemical factors during the bonding process. Quantitative …

Characterization of non-conductive paste materials (NCP) for thermocompression bonding in a Direct Bonded Heterogeneously Integrated (DBHi) Si-bridge package

…, C Marushima, H Mori, S Kohara, R Yu… - 2022 IEEE 72nd …, 2022 - ieeexplore.ieee.org
Direct Bonded Heterogeneous Integrated (DBHi) silicon-bridge packages use known
standard bond and assembly processes but require special considerations with regards to the …

Voids-free die-level Cu/ILD hybrid bonding

K Sakuma, R Yu, N Polomoff, L Darling… - 2023 IEEE 73rd …, 2023 - ieeexplore.ieee.org
Multiple moisture evolutions/adsorptions pathways on the dielectric film surfaces and in the
film bulk were linked to bonding voids contributions based on Zhuravlev model in silica. A die…

Current advancements in animal models of postsurgical lymphedema: a systematic review

JF Hsu, RP Yu, EW Stanton, J Wang… - Advances in Wound …, 2022 - liebertpub.com
Significance: Secondary lymphedema is a debilitating disease caused by lymphatic
dysfunction characterized by chronic swelling, dysregulated inflammation, disfigurement, and …

Hybrid lithography: The marriage between optical and e-beam lithography. A method to study process integration and device performance for advanced device nodes

…, DM Fried, AW Topol, JR Brancaccio, R Yu… - Microelectronic …, 2006 - Elsevier
Moore’s law continues to prescribe ever smaller device dimensions with each new device
node. While the new device nodes are scheduled at even pace, the innovation required to …

Small peptide modulation of fibroblast growth factor receptor 3-dependent postnatal lymphangiogenesis

…, E Jung, YJ Seong, EK Park, C Sung, R Yu… - … research and biology, 2019 - liebertpub.com
Background: The fibroblast growth factor receptor (FGFR) family includes transmembrane
receptors involved in a wide range of developmental and postdevelopmental biologic …