Striatal Models, Cellular Detail

KT Blackwell, S Damodaran, R Evans - Encyclopedia of Computational …, 2014 - Springer
… Another class of striatal models includes the complex models. These contain a large …
There are several models of striatal neurons that contain cellular detail (Table 1). These models

Modeling intracellular signaling underlying striatal function in health and disease

AG Nair, O Gutierrez-Arenas, O Eriksson… - Progress in molecular …, 2014 - Elsevier
Striatum, which is the input nucleus of the basal ganglia, … molecular and cellular properties
of striatal neurons and the … development of quantitative dynamical models for describing the …

Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease

X Gu, VM André, C Cepeda, SH Li, XJ Li… - Molecular …, 2007 - Springer
… We suggest that the cellular models are valuable for rapid identification of candidate molecular
mechanisms underlying both cell-autonomous and non-cell-autonomous toxicity of mhtt, …

The organization of the striatal output system: a single-cell juxtacellular labeling study in the rat

Y Wu, S Richard, A Parent - Neuroscience research, 2000 - Elsevier
… One of the central tenets of the current basal ganglia model is the segregation of the striatal
output pathways. Early retrograde cell labeling studies have supported the idea of distinct …

Physiology and pharmacology of striatal neurons

AC Kreitzer - Annual review of neuroscience, 2009 - annualreviews.org
striatal output. This review examines the cellular physiology and modulation of striatal neurons
… This review focuses on the cellular physiology of different striatal neuron types, including …

Neuronal types in the striatum of man

H Braak, E Braak - Cell and tissue research, 1982 - Springer
… There is no correlation between these numbers and the frequency in which the cell types
occur in the striatum, nor the frequency of successfully impregnated cellular images of a certain …

A spatiomolecular map of the striatum

A Märtin, D Calvigioni, O Tzortzi, J Fuzik, E Wärnberg… - Cell reports, 2019 - cell.com
… at the cellular level, we genetically labeled the Oprm1+ striatal … (O) Model of the spatial
definition of the striatum by the … in the anterior striatum (upper row) and posterior striatum (lower …

Striatal insights: a cellular and molecular perspective on repetitive behaviors in pathology

CL Burton, A Longaretti, A Zlatanovic… - Frontiers in Cellular …, 2024 - frontiersin.org
… They observed distinct changes between the striatal pathways in this autism model; iSPNs
show impairments in pre-and postsynaptic synaptic functions, synaptic plasticity, and spine …

The microcircuits of striatum in silico

JJJ Hjorth, A Kozlov, I Carannante… - Proceedings of the …, 2020 - pnas.org
… We focus on simulation at the striatal cellular/microcircuit level, in which the molecular/…
full-scale model of the mouse striatum using available data on synaptic connectivity, cellular

Towards an integration of biochemical and biophysical models of neuronal information processing: a case study in the nigro-striatal system

R Kotier, D Schirok - Reviews in the Neurosciences, 1999 - degruyterbrill.com
striatal neurons /18/, the cellular distribution of AC I, IV, VII, VIII, and IX within the striatum still
… used in our model are based on enzyme activities observed in rat striatal homogenate 727/ …