Conclusions With increasing age, the incidence and, thus, socioeconomic impact of AD are
growing. Increasing knowledge about the pathophysiologic mechanisms leading to AD has …

With the increasing life expectancy in developed countries, the incidence of Alzheimer’s
disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the …

Background: Histopathological studies and animal models suggest that hippocampal subfields
may be differently affected by aging, Alzheimer's disease (AD), and other diseases. High‐…

Context Most neuroimaging studies of posttraumatic stress disorder (PTSD) have focused on
potential abnormalities in the whole hippocampus, but the subfields of this structure, which …

Histopathological studies and animal models suggest that different physiological and
pathophysiological processes exert different subfield specific effects on the hippocampus. High‐…

Objective An increasing number of human in vivo magnetic resonance imaging (MRI) studies
have focused on examining the structure and function of the subfields of the hippocampal …

Animal studies suggest an involvement of CA3 and dentate gyrus (CA3&DG) in memory
encoding and early retrieval and an involvement of CA1 in late retrieval, consolidation and …

PURPOSE: Extrafocal structural abnormalities have been consistently described in temporal
lobe epilepsy (TLE) with mesial temporal lobe sclerosis (TLE-MTS). In TLE without MTS (…

BACKGROUND: Details of the internal hippocampal structure visible at 4 T allow for in vivo
volumetry of subfields. The aims of this study were: 1. To determine if Apo e4 has subfield …

Temporal lobe epilepsy ( TLE ) is the most common focal epilepsy in adults. TLE has a high
chance of becoming medically refractory, and as such, is frequently considered for further …