User profiles for Satoko Hori
Satoko HoriKeio University Faculty of Pharmacy Verified email at keio.jp Cited by 3625 |
A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro
Although tight‐junctions (TJs) at the blood–brain barrier (BBB) are important to prevent non‐specific
entry of compounds into the CNS, molecular mechanisms regulating TJ …
entry of compounds into the CNS, molecular mechanisms regulating TJ …
Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte‐derived soluble factor (s)
The purpose of the present study was to clarify the expression, transport properties and
regulation of ATP‐binding cassette G2 (ABCG2) transporter at the rat blood–brain barrier (BBB). …
regulation of ATP‐binding cassette G2 (ABCG2) transporter at the rat blood–brain barrier (BBB). …
A human IAP-family gene, apollon, expressed in human brain cancer cells
IAP is a family of protein that has baculovirus IAP repeat (BIR) domains and inhibits apoptosis.
We found a human IAP family gene, which we named Apollon, encoding a huge protein (…
We found a human IAP family gene, which we named Apollon, encoding a huge protein (…
Co‐administration of proton pump inhibitors delays elimination of plasma methotrexate in high‐dose methotrexate therapy
…, K Doki, M Homma, H Tamaki, S Hori… - British journal of …, 2009 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Co‐administration of proton pump
inhibitors (PPIs) increases plasma methotrexate (MTX) concentration in cancer patients …
inhibitors (PPIs) increases plasma methotrexate (MTX) concentration in cancer patients …
A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters
Physiological studies of the blood–brain barrier (BBB) are often performed in rats. We
describe the functional characterization of a reproducible in vitro model of the rat BBB and its …
describe the functional characterization of a reproducible in vitro model of the rat BBB and its …
Estimating the range of incremental cost-effectiveness thresholds for healthcare based on willingness to pay and GDP per capita: a systematic review
H Iino, M Hashiguchi, S Hori - PloS one, 2022 - journals.plos.org
Background Decision-making in healthcare policy involves assessing both costs and benefits.
In determining the cost-effectiveness (CE) threshold, willingness to pay (WTP) per quality-…
In determining the cost-effectiveness (CE) threshold, willingness to pay (WTP) per quality-…
New approaches to in vitro models of blood–brain barrier drug transport
The pharmaceutical industry has been searching for an in vitro blood-brain barrier (BBB) model
that preserves in vivo transporter functions in CNS drug discovery and development. The …
that preserves in vivo transporter functions in CNS drug discovery and development. The …
Distinct spatio‐temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain
M Tachikawa, M Watanabe, S Hori… - Journal of …, 2005 - Wiley Online Library
Using in situ hybridization for the mouse brain, we analyzed developmental changes in gene
expression for the ATP‐binding cassette (ABC) transporter subfamilies ABCA1–4 and 7, …
expression for the ATP‐binding cassette (ABC) transporter subfamilies ABCA1–4 and 7, …
Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study
…, N Takahashi, N Miyazaki, K Ishizuchi, S Hori… - The journal of headache …, 2023 - Springer
Background Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) are a
favourable option for patients with migraine who experience distressful headache disability …
favourable option for patients with migraine who experience distressful headache disability …
Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes
T Wada, S Hori, M Sugiyama… - American Journal …, 2010 - journals.physiology.org
Maternal insulin resistance is essential for efficient provision of glucose to the fetus. Although
elevation of placental hormones is known to relate to the development of insulin resistance, …
elevation of placental hormones is known to relate to the development of insulin resistance, …