User profiles for Satoko Hori

Satoko Hori

Keio University Faculty of Pharmacy
Verified email at keio.jp
Cited by 3625

A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro

S Hori, S Ohtsuki, K Hosoya… - Journal of …, 2004 - Wiley Online Library
Although tight‐junctions (TJs) at the blood–brain barrier (BBB) are important to prevent non‐specific
entry of compounds into the CNS, molecular mechanisms regulating TJ …

Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte‐derived soluble factor (s)

S Hori, S Ohtsuki, M Tachikawa… - Journal of …, 2004 - Wiley Online Library
The purpose of the present study was to clarify the expression, transport properties and
regulation of ATP‐binding cassette G2 (ABCG2) transporter at the rat blood–brain barrier (BBB). …

A human IAP-family gene, apollon, expressed in human brain cancer cells

Z Chen, M Naito, S Hori, T Mashima, T Yamori… - Biochemical and …, 1999 - Elsevier
IAP is a family of protein that has baculovirus IAP repeat (BIR) domains and inhibits apoptosis.
We found a human IAP family gene, which we named Apollon, encoding a huge protein (…

Co‐administration of proton pump inhibitors delays elimination of plasma methotrexate in high‐dose methotrexate therapy

…, K Doki, M Homma, H Tamaki, S Hori… - British journal of …, 2009 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Co‐administration of proton pump
inhibitors (PPIs) increases plasma methotrexate (MTX) concentration in cancer patients …

A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters

…, F Bourasset, S Cisternino, X Declèves, S Hori… - Brain research, 2007 - Elsevier
Physiological studies of the blood–brain barrier (BBB) are often performed in rats. We
describe the functional characterization of a reproducible in vitro model of the rat BBB and its …

Estimating the range of incremental cost-effectiveness thresholds for healthcare based on willingness to pay and GDP per capita: a systematic review

H Iino, M Hashiguchi, S Hori - PloS one, 2022 - journals.plos.org
Background Decision-making in healthcare policy involves assessing both costs and benefits.
In determining the cost-effectiveness (CE) threshold, willingness to pay (WTP) per quality-…

New approaches to in vitro models of blood–brain barrier drug transport

T Terasaki, S Ohtsuki, S Hori, H Takanaga… - Drug discovery today, 2003 - Elsevier
The pharmaceutical industry has been searching for an in vitro blood-brain barrier (BBB) model
that preserves in vivo transporter functions in CNS drug discovery and development. The …

Distinct spatio‐temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain

M Tachikawa, M Watanabe, S Hori… - Journal of …, 2005 - Wiley Online Library
Using in situ hybridization for the mouse brain, we analyzed developmental changes in gene
expression for the ATP‐binding cassette (ABC) transporter subfamilies ABCA1–4 and 7, …

Predicting response to CGRP-monoclonal antibodies in patients with migraine in Japan: a single-centre retrospective observational study

…, N Takahashi, N Miyazaki, K Ishizuchi, S Hori… - The journal of headache …, 2023 - Springer
Background Anti-calcitonin gene-related peptide monoclonal antibodies (CGRPmAbs) are a
favourable option for patients with migraine who experience distressful headache disability …

Progesterone inhibits glucose uptake by affecting diverse steps of insulin signaling in 3T3-L1 adipocytes

T Wada, S Hori, M Sugiyama… - American Journal …, 2010 - journals.physiology.org
Maternal insulin resistance is essential for efficient provision of glucose to the fetus. Although
elevation of placental hormones is known to relate to the development of insulin resistance, …