Long-acting neuraminidase inhibitor laninamivir octanoate as post-exposure prophylaxis for influenza

…, K Ishida, S Awamura, S Nishioka… - Reviews of Infectious …, 2016 - academic.oup.com
Background. A single administration of laninamivir octanoate, a long-acting neuraminidase
inhibitor, has been proven to be effective in the treatment of influenza but not for post-…

Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single …

H Itoh, S Ito, H Rakugi, Y Okuda, S Nishioka - Hypertension Research, 2019 - nature.com
The stimulation of mineralocorticoid receptors is linked to the development of hypertension
and cardiovascular or renal damage in patients with diabetes, and the blockade of these …

Adverse event signal extraction from cancer patients' narratives focusing on impact on their daily-life activities

S Nishioka, M Asano, S Yada, E Aramaki, H Yajima… - Scientific reports, 2023 - nature.com
Adverse event (AE) management is important to improve anti-cancer treatment outcomes, but
it is known that some AE signals can be missed during clinical visits. In particular, AEs that …

Identification of hand-foot syndrome from cancer patients' blog posts: BERT-based deep-learning approach to detect potential adverse drug reaction symptoms

S Nishioka, T Watanabe, M Asano, T Yamamoto… - PLoS …, 2022 - journals.plos.org
Early detection and management of adverse drug reactions (ADRs) is crucial for improving
patients’ quality of life. Hand-foot syndrome (HFS) is one of the most problematic ADRs for …

Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions

…, Y Wada, K Watanabe, R Yoshikawa, S Nishioka… - PLoS …, 2014 - journals.plos.org
Dendritic cells (DCs) play essential roles in both innate and adaptive immune responses. In
addition, mutual regulation of the nervous system and immune system is well studied. One of …

[HTML][HTML] Adverse event signal detection using patients' concerns in pharmaceutical care records: evaluation of deep learning models

S Nishioka, S Watabe, Y Yanagisawa… - Journal of medical …, 2024 - jmir.org
Background Early detection of adverse events and their management are crucial to
improving anticancer treatment outcomes, and listening to patients’ subjective opinions (patients’ …

[HTML][HTML] The cyclin-dependent kinase inhibitor p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia/reperfusion injury in mice

S Nishioka, D Nakano, K Kitada, T Sofue, H Ohsaki… - Kidney international, 2014 - Elsevier
The cyclin-dependent kinase inhibitor p21 plays important roles in chronic renal disorders;
however, its roles in response to acute renal stress are unclear. Here we evaluated p21 in …

Latent I g A deposition from donor kidneys does not affect transplant prognosis, irrespective of mesangial expansion

…, M Inui, T Hara, M Moritoki, S Nishioka… - Clinical …, 2013 - Wiley Online Library
Introduction Latent mesangial immunoglobulin A ( I g A ) deposition in the donated kidney
has been investigated in the context of kidney transplantation. However, few studies have …

Impact of FDG-PET findings on decisions regarding patient management strategies: a multicenter trial in patients with lung cancer and other types of cancer

…, M Koizumi, H Seto, M Kojo, S Nishioka… - Annals of nuclear …, 2015 - Springer
Objective To date, numerous studies have been conducted on the diagnostic capabilities of
positron emission tomography using [ 18 F]-fluorodeoxyglucose (FDG-PET). However, no …

Celiprolol reduces oxidative stress and attenuates left ventricular remodeling induced by hypoxic stress in mice

S Nishioka, T Yoshioka, A Nomura, R Kato… - Hypertension …, 2013 - nature.com
We have previously reported that intermittent hypoxic stress, which is relevant to sleep apnea
syndrome (SAS), increases oxidative stress and induces left ventricular (LV) remodeling. …