Intravenous immunoglobulin ameliorates ITP via activating Fcγ receptors on dendritic cells
V Siragam, AR Crow, D Brinc, S Song, J Freedman… - Nature medicine, 2006 - nature.com
Despite a more than 20-year experience of therapeutic benefit, the relevant molecular and
cellular targets of intravenous immunoglobulin (IVIg) in autoimmune disease remain unclear. …
cellular targets of intravenous immunoglobulin (IVIg) in autoimmune disease remain unclear. …
A framework for the general design and computation of hybrid neural networks
There is a growing trend to design hybrid neural networks (HNNs) by combining spiking
neural networks and artificial neural networks to leverage the strengths of both. Here, we …
neural networks and artificial neural networks to leverage the strengths of both. Here, we …
IVIg inhibits reticuloendothelial system function and ameliorates murine passive‐immune thrombocytopenia independent of anti‐idiotype reactivity
Although the mechanism of action of intravenous immunoglobulin (IVIg) in treating antibody‐dependent
thrombocytopenia remains unclear, most studies have suggested that IVIg …
thrombocytopenia remains unclear, most studies have suggested that IVIg …
Mechanisms of action of intravenous immunoglobulin in the treatment of immune thrombocytopenia
AR Crow, S Song, V Siragam… - Pediatric blood & …, 2006 - Wiley Online Library
Intravenous immunoglobulin (IVIG) is currently used to treat a multitude of autoimmune disorders
including immune thrombocytopenic purpura (ITP), yet the mechanism of action of IVIG …
including immune thrombocytopenic purpura (ITP), yet the mechanism of action of IVIG …
IVIg-mediated amelioration of murine ITP via FcγRIIB is independent of SHIP1, SHP-1, and Btk activity
AR Crow, S Song, J Freedman, CD Helgason… - Blood, 2003 - ashpublications.org
It has been established that amelioration of murine immune thrombocytopenia purpura (ITP)
by IVIg is dependent on the inhibitory receptor FcγRIIB. Co-cross-linking of the FcγRIIB with …
by IVIg is dependent on the inhibitory receptor FcγRIIB. Co-cross-linking of the FcγRIIB with …
Frequency analysis and clinical characterization of spinocerebellar ataxia types 1, 2, 3, 6, and 7 in Korean patients
WY Lee, DK Jin, MR Oh, JE Lee, SM Song… - Archives of …, 2003 - jamanetwork.com
Background By genetic analysis, the CAG repeat expansion has been established in
spinocerebellar ataxia (SCA) types 1, 2, 3, 6, and 7. Despite the genetic differentiation of SCA, the …
spinocerebellar ataxia (SCA) types 1, 2, 3, 6, and 7. Despite the genetic differentiation of SCA, the …
Can antibodies with specificity for soluble antigens mimic the therapeutic effects of intravenous IgG in the treatment of autoimmune disease?
V Siragam, D Brinc, AR Crow, S Song… - The Journal of clinical …, 2005 - jci.org
Intravenous Ig (IVIg) mediates protection from the effects of immune thrombocytopenic purpura
(ITP) as well as numerous other autoimmune states; however, the active antibodies within …
(ITP) as well as numerous other autoimmune states; however, the active antibodies within …
Monoclonal IgG can ameliorate immune thrombocytopenia in a murine model of ITP: an alternative to IVIG
S Song, AR Crow, J Freedman… - Blood, The Journal of …, 2003 - ashpublications.org
Intravenous immunoglobulin (IVIG) is used to treat immune thrombocytopenia resulting from
a variety of autoimmune and nonautoimmune diseases such as idiopathic …
a variety of autoimmune and nonautoimmune diseases such as idiopathic …
Interleukin-10 inhibits interferon-γ–induced intercellular adhesion molecule-1 gene transcription in human monocytes
S Song, H Ling-Hu, KA Roebuck… - Blood, The Journal …, 1997 - ashpublications.org
Interleukin-10 (IL-10) is a potent monocyte regulatory cytokine that inhibits gene expression
of proinflammatory mediators. In this study, we investigated the mechanism by which IL-10 …
of proinflammatory mediators. In this study, we investigated the mechanism by which IL-10 …
Identification of mutations in the GNPTA (MGC4170) gene coding for GlcNAc‐phosphotransferase α/β subunits in Korean patients with mucolipidosis type II or type IIIA
KH Paik, SM Song, CS Ki, HW Yu, JS Kim… - Human …, 2005 - Wiley Online Library
Mucolipidosis types II and III are autosomal recessive inherited diseases caused by a
deficiency in the lysosomal enzyme N‐acetylglucosamine‐1 phosphotransferase (GlcNAc‐…
deficiency in the lysosomal enzyme N‐acetylglucosamine‐1 phosphotransferase (GlcNAc‐…