H2S Signals Through Protein S-Sulfhydration
Hydrogen sulfide (H 2 S), a messenger molecule generated by cystathionine γ-lyase, acts
as a physiologic vasorelaxant. Mechanisms whereby H 2 S signals have been elusive. We …
as a physiologic vasorelaxant. Mechanisms whereby H 2 S signals have been elusive. We …
A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
S Kim, P Wong, PA Coulombe - Nature, 2006 - nature.com
Cell growth, an increase in mass and size, is a highly regulated cellular event. The Akt/mTOR
(mammalian target of rapamycin) signalling pathway has a central role in the control of …
(mammalian target of rapamycin) signalling pathway has a central role in the control of …
Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions
Nuclear factor κB (NF-κB) is an antiapoptotic transcription factor. We show that the antiapoptotic
actions of NF-κB are mediated by hydrogen sulfide (H 2 S) synthesized by cystathionine …
actions of NF-κB are mediated by hydrogen sulfide (H 2 S) synthesized by cystathionine …
[HTML][HTML] Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain
The inositol pyrophosphate IP7 (5-diphosphoinositolpentakisphosphate), formed by a family
of three inositol hexakisphosphate kinases (IP6Ks), modulates diverse cellular activities. We …
of three inositol hexakisphosphate kinases (IP6Ks), modulates diverse cellular activities. We …
How social media engagement leads to sports channel loyalty: Mediating roles of social presence and channel commitment
Social TV is defined as real-time backchannel communication on social networking sites (SNSs)
during a live television broadcast. Despite some pessimistic forecasts concerning the …
during a live television broadcast. Despite some pessimistic forecasts concerning the …
Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm
S Kim, PA Coulombe - Genes & development, 2007 - genesdev.cshlp.org
Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are encoded
by a large family of differentially expressed genes. Owing in part to their properties and …
by a large family of differentially expressed genes. Owing in part to their properties and …
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase
mTOR complex 1 (mTORC1; mammalian target of rapamycin [mTOR] in complex with raptor)
is a key regulator of protein synthesis and cell growth in response to nutrient amino acids. …
is a key regulator of protein synthesis and cell growth in response to nutrient amino acids. …
Emerging role for the cytoskeleton as an organizer and regulator of translation
S Kim, PA Coulombe - Nature reviews Molecular cell biology, 2010 - nature.com
The cytoskeleton is an intricate and dynamic fibrous network that has an essential role in
the generation and regulation of cell architecture and cellular mechanical properties. The …
the generation and regulation of cell architecture and cellular mechanical properties. The …
Pni: industrial anomaly detection using position and neighborhood information
Because anomalous samples cannot be used for training, many anomaly detection and
localization methods use pre-trained networks and non-parametric modeling to estimate …
localization methods use pre-trained networks and non-parametric modeling to estimate …
A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness
The switch between stem/progenitor cell expansion and differentiation is critical for organ
homeostasis. The mammalian Hippo pathway effector and oncoprotein YAP expands …
homeostasis. The mammalian Hippo pathway effector and oncoprotein YAP expands …