Fluorinated molecules as drugs and imaging agents in the CNS

S Sun, A Adejare - Current topics in medicinal chemistry, 2006 - benthamdirect.com
The strategic use of fluorine substitution in drug discovery and drug development is well
documented. The small size and high electronegativity of fluorine are among properties of this …

Computer-aided drug design to generate a unique antibiotic family

…, F Wu, JP Fernandez-Murray, E Lu, S Sun… - Nature …, 2024 - nature.com
The World Health Organization has identified antibiotic resistance as one of the three
greatest threats to human health. The need for antibiotics is a pressing matter that requires …

Identification of ferroptosis-related lncRNAs for predicting prognosis and immunotherapy response in non-small cell lung cancer

L Yuan, S Sun, Q Zhang, HT Li, Z Shen, C Hu… - Future Generation …, 2024 - Elsevier
Increasing evidences have demonstrated the ferroptosis-related lncRNAs are key regulators
of non- small cell lung cancer (NSCLC) progression and new targets for NSCLC therapy. …

[HTML][HTML] scRGCL: a cell type annotation method for single-cell RNA-seq data using residual graph convolutional neural network with contrastive learning

L Yuan, S Sun, Y Jiang, Q Zhang, L Ye… - Briefings in …, 2024 - journals.aai.org
Cell type annotation is a critical step in analyzing single-cell RNA sequencing (scRNA-seq)
data. A large number of deep learning (DL)–based methods have been proposed to …

A personalized ubiquitous education support environment by comparing learning instructional requirement with learner's behavior

Z Cheng, S Sun, M Kansen, T Huang… - … and Applications (AINA' …, 2005 - ieeexplore.ieee.org
With the progress of ubiquitous techniques and devices, such as RFID and sensors, etc.,
invisible computers are embedded in one's life and working environment, such as applicants, …

Structures of Two New Benzofuran Derivatives from the Bark of Mulberry Tree (Morus Macroura Miq.)

SG Sun, RY Chen, DQ Yu - Journal of Asian natural products …, 2001 - Taylor & Francis
Two new benzofuran derivatives, macrourins A (1) and B (2), together with two known
stilbene derivatives, were isolated from the barks of Morus macroura Miq. Their structures …

Syntheses and Pharmacological Evaluations of Novel N‐Substituted Bicyclo‐Heptane‐2‐amines at N‐Methyl‐d‐Aspartate Receptors

Z Ates‐Alagoz, S Sun, J Wallach… - Chemical biology & …, 2011 - Wiley Online Library
Several novel norcamphor (bicycloheptane)‐based compounds were designed and synthesized
as non‐competitive N‐methyl‐d‐aspartate receptor antagonists at the phencyclidine …

Experimental Study of Point Load Based on Close-Range Photogrammetry

T Sun, S Zhao, X Meng, Y Liu… - 2024 5th International …, 2024 - ieeexplore.ieee.org
At present, the area of the fracture surface is mostly obtained by equivalent approximation
method in point load tests. However, the area obtained by this method is not accurate enough …

A proposal on a learner's context-aware personalized education support method based on principles of behavior science

Z Cheng, Q Han, S Sun, M Kansen… - … -Volume 1 (AINA'06), 2006 - ieeexplore.ieee.org
With the progress of ubiquitous techniques and devices, such as RF-ID and sensors, etc.,
invisible computers are embedded in one's life and working environment, such as applicants, …

Syntheses and N-methyl-D-aspartate receptor antagonist pharmacology of fluorinated arylcycloheptylamines

S Sun, J Wallach, A Adejare - Medicinal Chemistry, 2014 - ingentaconnect.com
Selective uncompetitive antagonists of the phencyclidine (PCP) binding site of the N-methyl-D-aspartate
receptor (NMDAR) are known to have therapeutic potential as anticonvulsants …