Ionic tactile sensors (ITS) represent a new class of deformable sensory platforms that mimic
not only the tactile functions and topological structures but also the mechanotransduction …

Abstract Characterization of mice with cell-specific deletion or overexpression of the
mineralocorticoid receptor (MR) shed a new light on its role in health and disease. …

The proto-oncogene KRAS is mutated in a wide array of human cancers, most of which are
aggressive and respond poorly to standard therapies. Although the identification of specific …

Oncogenic mutations in the serine/threonine kinase B-RAF (also known as BRAF) are found
in 50–70% of malignant melanomas 1 . Pre-clinical studies have demonstrated that the B-…

To enable arrayed or pooled loss-of-function screens in a wide range of mammalian cell
types, including primary and nondividing cells, we are developing lentiviral short hairpin RNA (…

Flexible tactile sensors have shown significant importance in various applications, including
touch panels, artificial skins, human–machine interfaces, and wearable medical devices. …

Myc is an oncoprotein transcription factor that plays a prominent role in cancer. Like many
transcription factors, Myc is an unstable protein that is destroyed by ubiquitin (Ub)-mediated …

Diffuse large B cell lymphoma (DLBCL) is the most common form of blood cancer and is
characterized by a striking degree of genetic and clinical heterogeneity. This heterogeneity …

Intratumor heterogeneity is a major clinical problem because tumor cell subtypes display
variable sensitivity to therapeutics and may play different roles in progression. We previously …

Lineage-survival oncogenes are activated by somatic DNA alterations in cancers arising
from the cell lineages in which these genes play a role in normal development 1 , 2 . Here we …