Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
MP Mattson, TB Shea - Trends in neurosciences, 2003 - cell.com
Folate is a cofactor in one-carbon metabolism, during which it promotes the remethylation of
homocysteine – a cytotoxic sulfur-containing amino acid that can induce DNA strand …
homocysteine – a cytotoxic sulfur-containing amino acid that can induce DNA strand …
Calcium-activated neutral proteinase (calpain) system in aging and Alzheimer's disease.
…, T Honda, PS Mohan, TB Shea… - Annals of the New …, 1994 - europepmc.org
Calpains (CANPs) are a family of calcium-dependent cysteine proteases under complex
cellular regulation. By making selective limited proteolytic cleavages, they activate or alter the …
cellular regulation. By making selective limited proteolytic cleavages, they activate or alter the …
Bubble nucleation in magmas: a dominantly heterogeneous process?
T Shea - Journal of Volcanology and Geothermal Research, 2017 - Elsevier
… For the present work, surface tension was parameterized as a function of P H2O , T, and
melt composition, to fit the values compiled from the different experimental datasets, taking the …
melt composition, to fit the values compiled from the different experimental datasets, taking the …
Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement
BJ Walker, T Abeel, T Shea, M Priest, A Abouelliel… - PloS one, 2014 - journals.plos.org
Advances in modern sequencing technologies allow us to generate sufficient data to analyze
hundreds of bacterial genomes from a single machine in a single day. This potential for …
hundreds of bacterial genomes from a single machine in a single day. This potential for …
High-quality draft assemblies of mammalian genomes from massively parallel sequence data
…, BJ Walker, T Sharpe, G Hall, TP Shea… - Proceedings of the …, 2011 - pnas.org
Massively parallel DNA sequencing technologies are revolutionizing genomics by making it
possible to generate billions of relatively short (~100-base) sequence reads at very low cost. …
possible to generate billions of relatively short (~100-base) sequence reads at very low cost. …
Time to recovery, chronicity, and levels of psychopathology in major depression: a 5-year prospective follow-up of 431 subjects
…, W Coryell, RMA Hirschfeld, T Shea - Archives of general …, 1992 - jamanetwork.com
• The course of illness of 431 subjects with major depression participating in the National
Institute of Mental Health Collaborative Depression Study was prospectively observed for 5 …
Institute of Mental Health Collaborative Depression Study was prospectively observed for 5 …
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study: Presented …
…, NH Russell, JJ Reiffers, TC Shea… - Blood, The Journal …, 2002 - ashpublications.org
Blast crisis is the most advanced stage of chronic myelogenous leukemia (CML) and is
highly refractory to therapy. CML is caused by expression of the chimeric BCR-ABL tyrosine …
highly refractory to therapy. CML is caused by expression of the chimeric BCR-ABL tyrosine …
Lenalidomide after stem-cell transplantation for multiple myeloma
…, MC Pasquini, MM Horowitz, TC Shea… - … England Journal of …, 2012 - Mass Medical Soc
Background Data are lacking on whether lenalidomide maintenance therapy prolongs the
time to disease progression after autologous hematopoietic stem-cell transplantation in …
time to disease progression after autologous hematopoietic stem-cell transplantation in …
[HTML][HTML] Densely interconnected transcriptional circuits control cell states in human hematopoiesis
Though many individual transcription factors are known to regulate hematopoietic differentiation,
major aspects of the global architecture of hematopoiesis remain unknown. Here, we …
major aspects of the global architecture of hematopoiesis remain unknown. Here, we …
Clinical and epidemiologic features of primary HIV infection
T Schacker, AC Collier, J Hughes, T Shea… - Annals of internal …, 1996 - acpjournals.org
… T-cell subsets were measured by the Hematopathology Laboratory of the University of …
Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City. …
Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City. …