User profiles for T. Shea

Thomas Shea

- Verified email at uml.edu - Cited by 14013

Tal Shay

- Verified email at post.bgu.ac.il - Cited by 9720

Thomas Shea

- Verified email at hawaii.edu - Cited by 2778

Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders

MP Mattson, TB Shea - Trends in neurosciences, 2003 - cell.com
Folate is a cofactor in one-carbon metabolism, during which it promotes the remethylation of
homocysteine – a cytotoxic sulfur-containing amino acid that can induce DNA strand …

Calcium-activated neutral proteinase (calpain) system in aging and Alzheimer's disease.

…, T Honda, PS Mohan, TB Shea… - Annals of the New …, 1994 - europepmc.org
Calpains (CANPs) are a family of calcium-dependent cysteine proteases under complex
cellular regulation. By making selective limited proteolytic cleavages, they activate or alter the …

Bubble nucleation in magmas: a dominantly heterogeneous process?

T Shea - Journal of Volcanology and Geothermal Research, 2017 - Elsevier
… For the present work, surface tension was parameterized as a function of P H2O , T, and
melt composition, to fit the values compiled from the different experimental datasets, taking the …

Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement

BJ Walker, T Abeel, T Shea, M Priest, A Abouelliel… - PloS one, 2014 - journals.plos.org
Advances in modern sequencing technologies allow us to generate sufficient data to analyze
hundreds of bacterial genomes from a single machine in a single day. This potential for …

High-quality draft assemblies of mammalian genomes from massively parallel sequence data

…, BJ Walker, T Sharpe, G Hall, TP Shea… - Proceedings of the …, 2011 - pnas.org
Massively parallel DNA sequencing technologies are revolutionizing genomics by making it
possible to generate billions of relatively short (~100-base) sequence reads at very low cost. …

Time to recovery, chronicity, and levels of psychopathology in major depression: a 5-year prospective follow-up of 431 subjects

…, W Coryell, RMA Hirschfeld, T Shea - Archives of general …, 1992 - jamanetwork.com
• The course of illness of 431 subjects with major depression participating in the National
Institute of Mental Health Collaborative Depression Study was prospectively observed for 5 …

Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study: Presented …

…, NH Russell, JJ Reiffers, TC Shea… - Blood, The Journal …, 2002 - ashpublications.org
Blast crisis is the most advanced stage of chronic myelogenous leukemia (CML) and is
highly refractory to therapy. CML is caused by expression of the chimeric BCR-ABL tyrosine …

Lenalidomide after stem-cell transplantation for multiple myeloma

…, MC Pasquini, MM Horowitz, TC Shea… - … England Journal of …, 2012 - Mass Medical Soc
Background Data are lacking on whether lenalidomide maintenance therapy prolongs the
time to disease progression after autologous hematopoietic stem-cell transplantation in …

[HTML][HTML] Densely interconnected transcriptional circuits control cell states in human hematopoiesis

…, ME McConkey, N Habib, N Yosef, CY Chang, T Shay… - Cell, 2011 - cell.com
Though many individual transcription factors are known to regulate hematopoietic differentiation,
major aspects of the global architecture of hematopoiesis remain unknown. Here, we …

Clinical and epidemiologic features of primary HIV infection

T Schacker, AC Collier, J Hughes, T Shea… - Annals of internal …, 1996 - acpjournals.org
T-cell subsets were measured by the Hematopathology Laboratory of the University of …
Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City. …