The intestine is inhabited by a large microbial community consisting primarily of anaerobes
and, to a lesser extent, facultative anaerobes, such as Escherichia coli , which we have …

Every mammal on the planet is colonized with E. coli (1), as well as cold‐blooded animals (eg,
fish) at an appropriately warm temperature (2). We estimate there are 10 21 E. coli cells in …

Maintaining macrophage (MΦ) heterogeneity is critical to ensure intestinal tissue homeostasis
and host defense. The gut microbiota and host factors are thought to synergistically guide …

DNA arrays of the entire set of Escherichia coli genes were used to measure the genomic
expression patterns of cells growing in late logarithmic phase on minimal glucose medium and …

The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed
in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone …

Whole-genome expression profiling revealed Escherichia coli MG1655 genes induced by
growth on mucus, conditions designed to mimic nutrient availability in the mammalian intestine…

Bacterial transcriptional networks consist of hundreds of transcription factors and thousands
of promoters. However, the true complexity of transcription in a bacterial pathogen and the …

The Entner-Doudoroff pathway is now known to be very widely distributed in nature.
Biochemical and physiological studies show that the Entner-Doudoroff pathway can operate in a …

The carbon sources that support the growth of pathogenic Escherichia coli O157:H7 in the
mammalian intestine have not previously been investigated. In vivo, the pathogenic E. coli …

When conditions cause bacterial growth to stop, extensive reprogramming of physiology
and gene expression allows for the cell's survival. We used whole‐genome DNA arrays to …